Fig. 4

Expression of differentially expressed proteins by race in age- and stage-matched human prostate cancer specimens. In 12 age-and stage-matched prostate cancer specimen pairs extracted from TCGA without subtracting the non-malignant controls, (A) XRCC5 protein was found to be significantly different (p < 0.05) between African-American and Caucasian-American prostate cancer specimens and (B) RNA expression of CAV1 and MYH9 were found to be significantly different (p < 0.01 and <0.05, respectively) between African-American and Caucasian-American prostate cancer specimens. The p-values were generated using the “t.test” function in R. AA = African-American; ADAR = double-stranded RNA-specific adenosine deaminase; CA = Caucasian-American; CAV1 = caveolin-1; CTNNB1 = beta-catenin; MYH9 = myosin heavy chain-9; SRSF1 = serine/arginine-rich splicing factor 1; TCGA = The Cancer Genome Atlas; XRCC5 = X-ray repair cross-complementing protein 5