Fig. 2
Expression of MRS, Ki67, and, mTOR signaling proteins in the wild type mouse organs (a) and MRS expression in lung cancer and normal appearing adjacent lung tissue specimens (b-d). a Expression of MRS, mTOR signaling proteins, and Ki67 was evaluated by immunoblotting using tissue lysates from 8-week-old wild type C57BL/6 mice. IHC of MRS expression in (b) human adjacent normal lung tissue and (c) LSL-Kras G12D and LSL-Kras-G12D:p53fl/fl murine lung cancer tissue. d Immunoblot analysis of MRS expression and mTOR components in 12 pairs of lung cancer and adjacent normal appearing lung tissue lysates