Skip to main content

Table 1 Relationships between MCL-1 overexpression and clinicopathologic characteristics in patients with esophageal squamous cell carcinoma

From: Targeting MCL-1 sensitizes human esophageal squamous cell carcinoma cells to cisplatin-induced apoptosis

   MCL-1 p–value
Characteristics All cases Non-overexpression Over-expression  
Gender     1.0000
 Male 47 17 30  
 Female 2 1 1  
Age (years)     0.2436
  ≤ 60 25 7 18  
  > 60 24 11 13  
Location     0.4568
 Upper 4 2 2  
 Middle 26 7 19  
 Lower 19 8 11  
Initial clinical stage     0.2168
  ≤ IIa 16 8 8  
  > IIa 33 10 23  
Tumor size     0.3309
  < 5 cm 13 6 7  
  ≥ 5 cm 36 11 25  
Differentiation     0.3262
 Poorly 16 6 10  
 Moderately 18 4 14  
 Well 15 7 8  
Depth of invasion     0.0131*
 Submucosa 5 2 3  
 Muscularis 28 14 14  
 Adventia 16 1 15  
Nodal metastasis     0.0174*
 Absent 20 11 9  
 Present 29 6 23  
  1. p-value was calculated using Fisher’s exact test or Pearson’s χ2 test. *p < 0.05 indicates a significant association among the variables