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Table 1 Relationships between MCL-1 overexpression and clinicopathologic characteristics in patients with esophageal squamous cell carcinoma

From: Targeting MCL-1 sensitizes human esophageal squamous cell carcinoma cells to cisplatin-induced apoptosis

  

MCL-1

p–value

Characteristics

All cases

Non-overexpression

Over-expression

 

Gender

   

1.0000

 Male

47

17

30

 

 Female

2

1

1

 

Age (years)

   

0.2436

  ≤ 60

25

7

18

 

  > 60

24

11

13

 

Location

   

0.4568

 Upper

4

2

2

 

 Middle

26

7

19

 

 Lower

19

8

11

 

Initial clinical stage

   

0.2168

  ≤ IIa

16

8

8

 

  > IIa

33

10

23

 

Tumor size

   

0.3309

  < 5 cm

13

6

7

 

  ≥ 5 cm

36

11

25

 

Differentiation

   

0.3262

 Poorly

16

6

10

 

 Moderately

18

4

14

 

 Well

15

7

8

 

Depth of invasion

   

0.0131*

 Submucosa

5

2

3

 

 Muscularis

28

14

14

 

 Adventia

16

1

15

 

Nodal metastasis

   

0.0174*

 Absent

20

11

9

 

 Present

29

6

23

 
  1. p-value was calculated using Fisher’s exact test or Pearson’s χ2 test. *p < 0.05 indicates a significant association among the variables
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BMC Cancer

ISSN: 1471-2407

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