Fig. 6From: Targeting MCL-1 sensitizes human esophageal squamous cell carcinoma cells to cisplatin-induced apoptosissiRNA silencing of MCL-1 sensitizes cisplatin-induced apoptosis in KYSE150 and KYSE510 cell lines. a, b KYSE150 (a) and KYSE510 (b) cells were transiently transfected with si-Ctrl or si-MCL-1 for 24 h, followed by exposure to 2 μM cisplatin for 48 h. After treatment, attached and floating cells were harvested and Western blot analysis for MCL-1, cleaved PARP and cleaved caspase-3 were performed. β-actin was use as a loading control. Arrow head: 17KD or 19 KD of cleaved caspase-3Back to article page