Table 4 OS and PFS (all patients)
Median OS (months) | Median PFS (months) | |||||||
|---|---|---|---|---|---|---|---|---|
Protein Expression | Low | High | P-value | Low | High | P-value | ||
ERCC1 | 21.4 | 10.5 | 0.006 | 10.2 | 5.1 | 0.027 | ||
COX2 | 17.7 | 10.5 | 0.051 | 6.5 | 5.2 | 0.463 | ||
Tubulin B3 | 11.6 | 11.9 | 0.704 | 6 | 6 | 0.347 | ||
CD4 | 11.9 | 11.9 | 0.446 | 5.6 | 8.8 | 0.253 | ||
CD8 | 13.5 | 8.6 | 0.041 | 6 | 3.9 | 0.766 | ||
SNPs | ||||||||
MDR1 C3435T | CC | TT | CT | P-value | CC | TT | CT | P-value |
20.2 | 16.5 | 10.5 | 0.19 | 7.9 | 6.6 | 6 | 0.654 | |
MDR1 G2677 T | GG | TT | GT | GG | TT | GT | ||
8.6 | 3.6 | 17.7 | 0.119 | 5.1 | 2.9 | 8.6 | 0.027 | |
ERCC1C8092A | AA | CC | CA | AA | CC | CA | ||
25.2 | 11.6 | 15.4 | 0.756 | 2.8 | 6 | 6 | 0.543 | |
ERCC1 N118 N | CC | TT | CT | CC | TT | CT | ||
8.2 | 21.4 | 8.5 | 0.063 | 5.2 | 8.8 | 3.9 | 0.006 | |