Table 3 Clinicopathological features of hepatocellular carcinomas with positive YAP1 expression (N = 624)
N (%) | p-value | ||
|---|---|---|---|
Sex | Male[518] vs. Female[106] | 16(3) vs. 4 (4) | 0.715 |
Age (yr) | ≤55[324] vs. >55[300] | 9(3) vs. 11 (4) | 0.681 |
Size (cm) | ≤5.0[379] vs. >5.0[235] | 12(3) vs. 8 (3) | 0.872 |
Multiplicity | Single[449] vs. Multiple[169] | 11(2) vs. 9 (5) | 0.072 |
Vascular invasion | Absent[330] vs. Present[286] | 10(3) vs. 10 (3) | 0.745 |
Large vessel invasion | Absent[578] vs. Present[37] | 18(3) vs. 2 (5) | 0.446 |
pT stage (AJCC 7th) | pT1–2[486] vs. pT3–4[138] | 16(3) vs. 4 (3) | 0.982 |
ES nuclear grade | 1–2[300] vs. 3–4[313] | 4(1) vs. 15 (5) | 0.014* |
Preoperative treatment | Done[261] vs. Not done[315] | 13(5) vs. 6 (2) | 0.114 |
Serum AFP (ng/ml) | ≤32[309] vs. >32[289] | 4(1) vs. 14 (5) | 0.011* |
Cell type | Hepatic[539] vs. Non-hepatic[61] | 17(3) vs. 2 (3) | 0.958 |
Histologic pattern | Trabecular/acinar[487] vs. Compact[113] | 12(2) vs. 7 (6) | 0.041* |
Desmoplastic stroma | Absent[462] vs. Present[113] | 9(2) vs. 9 (8) | <0.001* |
Expression of CK19 | Negative[523] vs. Positive[101] | 10(2) vs. 10 (10) | <0.001* |
Etiology of CLD | Viral[557] vs. Non-viral[36] | 19(3) vs. 0 (0) | 0.621 |