Table 1 Patient demographics (N = 913)
HCC (624) | cHC-CCA (31) | IHCCA (239) | EHBCA (19) | p-value | |||
|---|---|---|---|---|---|---|---|
Stem cell (16) | Classical (15) | CLC(24) | Non-CLC(215) | ||||
Sex (M:F ratio) | 4.9 | 2.2 | 14 | 2 | 2.9 | 1.1 | 0.001* |
Male | 518(83) | 11(69) | 14(93) | 16(67) | 160(74) | 10(53) | 0.001* |
Female | 106(17) | 5(31) | 1(7) | 8(33) | 55(26) | 9(47) | |
Age (year, mean ± SD) | 54 ± 10 | 51 ± 12 | 58 ± 8 | 60 ± 10 | 62 ± 9 | 58 ± 12 | <0.001* |
Chronic liver disease | 593(95) | 16(100) | 12(80) | 12(50) | 39(18) | 0(0) | <0.001* |
Viral | 557(94) | 10(63) | 9(75) | 7(58) | 27(69) | 0(0) | <0.001* |
Non-viral | 36(6) | 5(31) | 3(25) | 5(42) | 12(31) | 0(0) | |
pT stage (AJCC 7th) | |||||||
pT1 | 256(41) | 9(56) | 3(20) | 7(29) | 81(38) | 1(5) | 0.01* |
pT2-pT4 | 360(58) | 7(44) | 12(80) | 17(71) | 131(61) | 17(89) | |
Progress | |||||||
Recur or metastasis | 395(63) | 7(44) | 10(67) | 11(46) | 144(67) | 12(63) | <0.001* |
PFS (median, month) | 26 | 103 | 12 | NA | 11 | 20 | <0.001* |
Death | |||||||
Deceased | 352(56) | 6(38) | 10(67) | 6(25) | 110(51) | 18(95) | <0.001* |
OS (median, month) | 77 | 91 | 21 | NA | 61 | 18 | <0.001* |