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Table 5 Number needed to test to identify one mutation carrier according to test criteria

From: Current guidelines for BRCA testing of breast cancer patients are insufficient to detect all mutation carriers

Test criteria

Mutation frequency

Number needed to test (NNT) to identify one mutation carrier

BC < 50 years

10/116 = 8.6%

12

BC < 60 years

13/235 = 5.5%

18

TNBC

5/35 = 14%

7

NBCG criteria

12/147 = 8.2%

12

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BMC Cancer

ISSN: 1471-2407

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