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Table 2 Differential expression of target genes in ovarian and fallopian tube cells

From: Characterization of MicroRNA-200 pathway in ovarian cancer and serous intraepithelial carcinoma of fallopian tube

 

Ovarian cells

Fallopian tube cells

Target genes

Overall

P-value

BNT

BOT

NSMT

SMT

CCL

Ov_ST

Overall p-value

STIC

FT_ST

Difference in medians against normal cells (P-value)

Difference in medians against normal cells (P-value)

ZEB1

<0.0005†

1.065 (0.336)

−0.880 (0.330)

−1.075 (0.156)

−0.602 (0.684)

−3.691 (0.048*)

0.925 (0.048*)

0.034†

−0.770 (0.458)

2.594 (0.114)

ZEB2

<0.0005†

1.167 (0.102)

−1.418 (0.048*)

−1.426 (0.002*)

−0.496 (0.516)

−4.083 (0.001*)

1.176 (0.012*)

0.034†

0.409 (0.458)

2.679 (0.114)

TGFB1

0.001†

−1.426 (0.234)

−1.009 (0.036*)

−1.669 (0.001*)

−0.902 (0.006*)

−0.129 (1.000)

−0.389 (1.000)

0.043†

−0.523 (0.800)

1.409 (0.114)

TGFB2

0.014†

−0.031 (1.000)

−0.718 (0.216)

−2.039 (0.006*)

−1.522 (0.012*)

−1.869 (0.282)

−0.819 (0.174)

0.352

−1.088 (0.800)

−0.812 (0.800)

  1. †significant at the 0.05 level by Kruskal Wallis test
  2. *significant at the 0.05 level by Mann-Whitney test (corrected using the Bonferroni method for multiple comparisons)