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Table 1 Differential expression of miR-200 and miR-205 in ovarian and fallopian tube cells

From: Characterization of MicroRNA-200 pathway in ovarian cancer and serous intraepithelial carcinoma of fallopian tube

  Ovarian cells Fallopian tube cells
MicroRNA Overall
P-value
BNT BOT NSMT SMT CCL Ov_ST Overall p-value STIC FT_ST
Difference in medians against normal cells (P-value) Difference in medians against normal cells (P-value)
MiR-200a <0.0005 1.807 (1.000) 2.839 (0.003*) 3.206 (0.001*) 3.081 (0.001*) 2.440 (0.002*) −1.612 (0.672) 0.018 2.613 (0.114) −1.227 (0.114)
MiR-200b <0.0005 −0.160 (1.000) 2.537 (0.006*) 2.544 (0.001*) 3.060 (0.001*) 4.051 (0.001*) −2.797 (0.396) 0.050 2.970 (0.114) −0.572 (1.000)
MiR-200c <0.0005 2.280 (0.060) 4.231 (0.004*) 4.516 (0.001*) 5.729 (0.001*) 5.919 (0.006*) −1.120 (1.000) 0.055 4.331 (0.114) 0.450 (1.000)
MiR-141 <0.0005 2.315 (0.030*) 3.978 (0.003*) 4.335 (0.001*) 4.412 (0.001*) 2.738 (0.001*) −1.310 (1.000) 0.034 4.883 (0.114) 1.702 (0.458)
MiR-429 <0.0005 1.241 (1.000) 2.295 (0.005*) 2.825 (0.001*) 2.090 (0.004*) 1.664 (0.004*) −2.897 (0.270) 0.047 5.204 (0.114) 2.370 (1.000)
MiR-205 0.001 −1.622 (1.000) 5.396 (0.792) 0.912 (1.000) 2.725 (0.030*) 8.156 (0.002*) −1.664 (1.000) 0.021 4.861 (0.114) 0.280 (0.458)
  1. BNT Benign tumors, BOT Borderline tumors, NSMT Non-Serous malignant tumors, SMT Serous malignant tumors, CCL Cancer cell lines, Ov_ST Ovarian stroma, STIC Serous tubal intraepithelial carcinoma, FT_ST Fallopian tube stroma
  2. significant at the 0.05 level by Kruskal Wallis test
  3. *significant at the 0.05 level by Mann-Whitney test (corrected using the Bonferroni method for multiple comparisons)