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Table 1 Differential expression of miR-200 and miR-205 in ovarian and fallopian tube cells

From: Characterization of MicroRNA-200 pathway in ovarian cancer and serous intraepithelial carcinoma of fallopian tube

 

Ovarian cells

Fallopian tube cells

MicroRNA

Overall

P-value

BNT

BOT

NSMT

SMT

CCL

Ov_ST

Overall p-value

STIC

FT_ST

Difference in medians against normal cells (P-value)

Difference in medians against normal cells (P-value)

MiR-200a

<0.0005†

1.807 (1.000)

2.839 (0.003*)

3.206 (0.001*)

3.081 (0.001*)

2.440 (0.002*)

−1.612 (0.672)

0.018†

2.613 (0.114)

−1.227 (0.114)

MiR-200b

<0.0005†

−0.160 (1.000)

2.537 (0.006*)

2.544 (0.001*)

3.060 (0.001*)

4.051 (0.001*)

−2.797 (0.396)

0.050†

2.970 (0.114)

−0.572 (1.000)

MiR-200c

<0.0005†

2.280 (0.060)

4.231 (0.004*)

4.516 (0.001*)

5.729 (0.001*)

5.919 (0.006*)

−1.120 (1.000)

0.055

4.331 (0.114)

0.450 (1.000)

MiR-141

<0.0005†

2.315 (0.030*)

3.978 (0.003*)

4.335 (0.001*)

4.412 (0.001*)

2.738 (0.001*)

−1.310 (1.000)

0.034†

4.883 (0.114)

1.702 (0.458)

MiR-429

<0.0005†

1.241 (1.000)

2.295 (0.005*)

2.825 (0.001*)

2.090 (0.004*)

1.664 (0.004*)

−2.897 (0.270)

0.047†

5.204 (0.114)

2.370 (1.000)

MiR-205

0.001†

−1.622 (1.000)

5.396 (0.792)

0.912 (1.000)

2.725 (0.030*)

8.156 (0.002*)

−1.664 (1.000)

0.021†

4.861 (0.114)

0.280 (0.458)

  1. BNT Benign tumors, BOT Borderline tumors, NSMT Non-Serous malignant tumors, SMT Serous malignant tumors, CCL Cancer cell lines, Ov_ST Ovarian stroma, STIC Serous tubal intraepithelial carcinoma, FT_ST Fallopian tube stroma
  2. †significant at the 0.05 level by Kruskal Wallis test
  3. *significant at the 0.05 level by Mann-Whitney test (corrected using the Bonferroni method for multiple comparisons)