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Table 3 Risk of non-Hodgkin and Hodgkin lymphoma subtypes according to smoking habits

From: The dose-response relationship between tobacco smoking and the risk of lymphomas: a case-control study

 

Smoking habitsa

χ2 for trend

Neverb

Current

 

<15 cig/day

≥15 cig/day

No.

No.

OR (95% CI)

No.

OR

95% CI

Non-Hodgkin lymphoma

 Mature B-cell lymphomas

219

67

0.95 (0.67–1.34)

95

1.37 (0.97–1.92)

p = 0.09

  DLBCL

133

33

0.76 (0.49–1.18)

49

1.09 (0.72–1.66)

p = 0.88

  Burkitt

5

4

3.07 (0.74–12.81)

4

3.30 (0.71–15.28)

p = 0.16

  Follicular

39

18

1.31 (0.69–2.47)

25

2.43 (1.31–4.51)

p < 0.01

  Mantle cell

4

1

0.66 (0.07–6.41)

2

1.04 (0.17–6.50)

p = 0.99

  Marginal zone

16

3

0.66 (0.18–2.44)

4

1.09 (0.33–3.66)

p = 0.80

  Lymphoplasmacytic

8

3

1.56 (0.38–6.48)

2

0.87 (0.16–4.86)

p = 0.99

  SLL/CLL

8

4

1.41 (0.40–4.93)

7

2.47 (0.81–7.59)

p = 0.06

  Other B-cell lymphomas

6

1

0.45 (0.05–4.15)

2

2.87 (0.41–20.02)

p = 0.46

 Mature T-cell lymphomas

14

8

1.83 (0.72–4.62)

6

1.72 (0.59–5.03)

p = 0.15

 Other or NOS

6

3

1.20 (0.75–1.91)

7

2.30 (1.40–3.77)

p < 0.01

Hodgkin lymphoma

 Nodular sclerosis

61

28

1.14 (0.61–2.12)

18

1.76 (0.78–3.98)

p = 0.23

 Mixed cellularity

6

2

1.02 (0.16–6.66)

10

5.60 (1.31–23.97)

p = 0.03

 Other or NOS

18

6

0.78 (0.27–2.21)

15

3.22 (1.15–9.04)

p = 0.06

  1. Odds ratios (OR) and 95% confidence intervals (CI) were estimated using unconditional logistic regression model adjusted for gender, age, study center, years of education, and place of birth
  2. CLL Chronic lymphocytic leukemia, DLBCL Diffuse large B-cell lymphoma, NOS Not otherwise specified, SLL Small lymphocytic lymphoma
  3. aFormer smokers excluded. bReference category