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Table 3 Risk of non-Hodgkin and Hodgkin lymphoma subtypes according to smoking habits

From: The dose-response relationship between tobacco smoking and the risk of lymphomas: a case-control study

  Smoking habitsa χ2 for trend
Neverb Current
  <15 cig/day ≥15 cig/day
No. No. OR (95% CI) No. OR 95% CI
Non-Hodgkin lymphoma
 Mature B-cell lymphomas 219 67 0.95 (0.67–1.34) 95 1.37 (0.97–1.92) p = 0.09
  DLBCL 133 33 0.76 (0.49–1.18) 49 1.09 (0.72–1.66) p = 0.88
  Burkitt 5 4 3.07 (0.74–12.81) 4 3.30 (0.71–15.28) p = 0.16
  Follicular 39 18 1.31 (0.69–2.47) 25 2.43 (1.31–4.51) p < 0.01
  Mantle cell 4 1 0.66 (0.07–6.41) 2 1.04 (0.17–6.50) p = 0.99
  Marginal zone 16 3 0.66 (0.18–2.44) 4 1.09 (0.33–3.66) p = 0.80
  Lymphoplasmacytic 8 3 1.56 (0.38–6.48) 2 0.87 (0.16–4.86) p = 0.99
  SLL/CLL 8 4 1.41 (0.40–4.93) 7 2.47 (0.81–7.59) p = 0.06
  Other B-cell lymphomas 6 1 0.45 (0.05–4.15) 2 2.87 (0.41–20.02) p = 0.46
 Mature T-cell lymphomas 14 8 1.83 (0.72–4.62) 6 1.72 (0.59–5.03) p = 0.15
 Other or NOS 6 3 1.20 (0.75–1.91) 7 2.30 (1.40–3.77) p < 0.01
Hodgkin lymphoma
 Nodular sclerosis 61 28 1.14 (0.61–2.12) 18 1.76 (0.78–3.98) p = 0.23
 Mixed cellularity 6 2 1.02 (0.16–6.66) 10 5.60 (1.31–23.97) p = 0.03
 Other or NOS 18 6 0.78 (0.27–2.21) 15 3.22 (1.15–9.04) p = 0.06
  1. Odds ratios (OR) and 95% confidence intervals (CI) were estimated using unconditional logistic regression model adjusted for gender, age, study center, years of education, and place of birth
  2. CLL Chronic lymphocytic leukemia, DLBCL Diffuse large B-cell lymphoma, NOS Not otherwise specified, SLL Small lymphocytic lymphoma
  3. aFormer smokers excluded. bReference category