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Fig. 3 | BMC Cancer

Fig. 3

From: Antiangiogenic agents targeting different angiogenic pathways have opposite effects on tumor hypoxia in R-18 human melanoma xenografts

Fig. 3

Vascular function. a-c, Blood supply time (BST) images and the corresponding BST frequency distributions of untreated (a), properdistatin-treated (b), and sunitinib-treated R-18 tumors (c). Color bars, BST scale in seconds; vertical lines, median BST; scale bars, 1 mm. The BST image of the untreated R-18 tumor (a) was produced from the first-pass imaging movie shown in Additional file 1. d, Median BST in untreated, properdistatin-treated, and sunitinib-treated R-18 tumors. Columns, means of 4–9 tumors; bars, SE

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