TY - JOUR AU - Zhu, J. AU - Nathan, C. AU - Jin, W. AU - Sim, D. AU - Ashcroft, G. S. AU - Wahl, S. M. PY - 2002 DA - 2002// TI - Conversion of proepithelin to epithelins: roles of SLPI and elastase in host defense and wound repair JO - Cell VL - 111 UR - https://doi.org/10.1016/S0092-8674(02)01141-8 DO - 10.1016/S0092-8674(02)01141-8 ID - Zhu2002 ER - TY - JOUR AU - Baker, M. AU - Mackenzie, I. R. AU - Pickering-Brown, S. M. AU - Gass, J. AU - Rademakers, R. AU - Lindholm, C. PY - 2006 DA - 2006// TI - Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17 JO - Nature VL - 442 UR - https://doi.org/10.1038/nature05016 DO - 10.1038/nature05016 ID - Baker2006 ER - TY - JOUR AU - Cruts, M. AU - Gijselinck, I. AU - Zee, J. AU - Engelborghs, S. AU - Wils, H. AU - Pirici, D. PY - 2006 DA - 2006// TI - Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21 JO - Nature VL - 442 UR - https://doi.org/10.1038/nature05017 DO - 10.1038/nature05017 ID - Cruts2006 ER - TY - JOUR AU - Daniel, R. AU - Daniels, E. AU - He, Z. AU - Bateman, A. PY - 2003 DA - 2003// TI - Progranulin (acrogranin/PC cell-derived growth factor/granulin-epithelin precursor) is expressed in the placenta, epidermis, microvasculature, and brain during murine development JO - Dev Dyn VL - 227 UR - https://doi.org/10.1002/dvdy.10341 DO - 10.1002/dvdy.10341 ID - Daniel2003 ER - TY - JOUR AU - He, Z. AU - Ong, C. H. AU - Halper, J. AU - Bateman, A. PY - 2003 DA - 2003// TI - Progranulin is a mediator of the wound response JO - Nat Med VL - 9 UR - https://doi.org/10.1038/nm816 DO - 10.1038/nm816 ID - He2003 ER - TY - JOUR AU - Bateman, A. AU - Bennett, H. P. PY - 2009 DA - 2009// TI - The granulin gene family: from cancer to dementia JO - BioEssays VL - 31 UR - https://doi.org/10.1002/bies.200900086 DO - 10.1002/bies.200900086 ID - Bateman2009 ER - TY - JOUR AU - Cheung, S. T. AU - Wong, S. Y. AU - Leung, K. L. AU - Chen, X. AU - So, S. AU - Ng, I. O. PY - 2004 DA - 2004// TI - Granulin-epithelin precursor overexpression promotes growth and invasion of hepatocellular carcinoma JO - Clin Cancer Res. VL - 10 UR - https://doi.org/10.1158/1078-0432.CCR-04-0960 DO - 10.1158/1078-0432.CCR-04-0960 ID - Cheung2004 ER - TY - JOUR AU - Cheung, S. T. AU - Cheung, P. F. AU - Cheng, C. K. AU - Wong, N. C. AU - Fan, S. T. PY - 2011 DA - 2011// TI - Granulin-epithelin precursor and ATP-dependent binding cassette (ABC)B5 regulate liver cancer cell chemoresistance JO - Gastroenterology VL - 140 UR - https://doi.org/10.1053/j.gastro.2010.07.049 DO - 10.1053/j.gastro.2010.07.049 ID - Cheung2011 ER - TY - JOUR AU - Cheung, P. F. AU - Yip, C. W. AU - Wong, N. C. AU - Fong, D. Y. AU - Ng, L. W. AU - Wan, A. M. PY - 2014 DA - 2014// TI - Granulin-epithelin precursor renders hepatocellular carcinoma cells resistant to natural killer cytotoxicity JO - Cancer Immunol Res VL - 2 UR - https://doi.org/10.1158/2326-6066.CIR-14-0096 DO - 10.1158/2326-6066.CIR-14-0096 ID - Cheung2014 ER - TY - JOUR AU - El-Serag, H. B. AU - Rudolph, K. L. PY - 2007 DA - 2007// TI - Hepatocellular carcinoma: epidemiology and molecular carcinogenesis JO - Gastroenterology VL - 132 UR - https://doi.org/10.1053/j.gastro.2007.04.061 DO - 10.1053/j.gastro.2007.04.061 ID - El-Serag2007 ER - TY - BOOK PY - 2015 DA - 2015// TI - Global Cancer Facts & Figures 3rd edition PB - American Cancer Society CY - Atlanta ID - ref11 ER - TY - JOUR AU - Yeo, W. AU - Mok, T. S. AU - Zee, B. AU - Leung, T. W. AU - Lai, P. B. AU - Lau, W. Y. PY - 2005 DA - 2005// TI - A randomized phase III study of doxorubicin versus cisplatin/interferon alpha-2b/doxorubicin/fluorouracil (PIAF) combination chemotherapy for unresectable hepatocellular carcinoma JO - J Natl Cancer Inst VL - 97 UR - https://doi.org/10.1093/jnci/dji315 DO - 10.1093/jnci/dji315 ID - Yeo2005 ER - TY - JOUR AU - Cao, H. AU - Phan, H. AU - Yang, L. X. PY - 2012 DA - 2012// TI - Improved chemotherapy for hepatocellular carcinoma JO - Anticancer Res VL - 32 ID - Cao2012 ER - TY - JOUR AU - Fan, S. T. AU - Mau Lo, C. AU - Poon, R. T. AU - Yeung, C. AU - Leung Liu, C. AU - Yuen, W. K. PY - 2011 DA - 2011// TI - Continuous improvement of survival outcomes of resection of hepatocellular carcinoma: a 20-year experience JO - Ann Surg VL - 253 UR - https://doi.org/10.1097/SLA.0b013e3182111195 DO - 10.1097/SLA.0b013e3182111195 ID - Fan2011 ER - TY - JOUR AU - Seeff, L. B. AU - Hoofnagle, J. H. PY - 2006 DA - 2006// TI - Epidemiology of hepatocellular carcinoma in areas of low hepatitis B and hepatitis C endemicity JO - Oncogene VL - 25 UR - https://doi.org/10.1038/sj.onc.1209560 DO - 10.1038/sj.onc.1209560 ID - Seeff2006 ER - TY - BOOK PY - 2015 DA - 2015// TI - Cancer Facts & Figures 2015 PB - American Cancer Society CY - Atlanta ID - ref16 ER - TY - JOUR AU - Ho, J. C. AU - Ip, Y. C. AU - Cheung, S. T. AU - Lee, Y. T. AU - Chan, K. F. AU - Wong, S. Y. PY - 2008 DA - 2008// TI - Granulin-epithelin precursor as a therapeutic target for hepatocellular carcinoma JO - Hepatology VL - 47 UR - https://doi.org/10.1002/hep.22191 DO - 10.1002/hep.22191 ID - Ho2008 ER - TY - JOUR AU - Wong, N. C. AU - Cheung, P. F. AU - Yip, C. W. AU - Chan, K. F. AU - Ng, I. O. AU - Fan, S. T. PY - 2014 DA - 2014// TI - Antibody against granulin-epithelin precursor sensitizes hepatocellular carcinoma to chemotherapeutic agents JO - Mol Cancer Ther VL - 13 UR - https://doi.org/10.1158/1535-7163.MCT-14-0012 DO - 10.1158/1535-7163.MCT-14-0012 ID - Wong2014 ER - TY - JOUR AU - Yip, C. W. AU - Cheung, P. F. AU - Leung, I. C. AU - Wong, N. C. AU - Cheng, C. K. AU - Fan, S. T. PY - 2014 DA - 2014// TI - Granulin-epithelin precursor interacts with heparan sulfate on liver cancer cells JO - Carcinogenesis VL - 35 UR - https://doi.org/10.1093/carcin/bgu164 DO - 10.1093/carcin/bgu164 ID - Yip2014 ER - TY - JOUR AU - Lam, C. Y. AU - Yip, C. W. AU - Poon, T. C. AU - Cheng, C. K. AU - Ng, E. W. AU - Wong, N. C. PY - 2012 DA - 2012// TI - Identification and characterization of tropomyosin 3 associated with granulin-epithelin precursor in human hepatocellular carcinoma JO - PLoS One VL - 7 UR - https://doi.org/10.1371/journal.pone.0040324 DO - 10.1371/journal.pone.0040324 ID - Lam2012 ER - TY - JOUR AU - Ng, P. C. AU - Ang, I. L. AU - Chiu, R. W. AU - Li, K. AU - Lam, H. S. AU - Wong, R. P. PY - 2010 DA - 2010// TI - Host-response biomarkers for diagnosis of late-onset septicemia and necrotizing enterocolitis in preterm infants JO - J Clin Invest VL - 120 UR - https://doi.org/10.1172/JCI40196 DO - 10.1172/JCI40196 ID - Ng2010 ER - TY - JOUR AU - Xia, X. AU - Serrero, G. PY - 1998 DA - 1998// TI - Identification of cell surface binding sites for PC-cell-derived growth factor, PCDGF, (epithelin/granulin precursor) on epithelial cells and fibroblasts JO - BiochemBiophys Res Commun VL - 245 UR - https://doi.org/10.1006/bbrc.1998.8498 DO - 10.1006/bbrc.1998.8498 ID - Xia1998 ER - TY - JOUR AU - Shuda, M. AU - Kondoh, N. AU - Imazeki, N. AU - Tanaka, K. AU - Okada, T. AU - Mori, K. PY - 2003 DA - 2003// TI - Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis JO - J Hepatol VL - 38 UR - https://doi.org/10.1016/S0168-8278(03)00029-1 DO - 10.1016/S0168-8278(03)00029-1 ID - Shuda2003 ER - TY - JOUR AU - Luk, J. M. AU - Lam, C. T. AU - Siu, A. F. AU - Lam, B. Y. AU - Ng, I. O. AU - Hu, M. Y. PY - 2006 DA - 2006// TI - Proteomic profiling of hepatocellular carcinoma in Chinese cohort reveals heat-shock proteins (Hsp27, Hsp70, GRP78) up-regulation and their associated prognostic values JO - Proteomics VL - 6 UR - https://doi.org/10.1002/pmic.200500306 DO - 10.1002/pmic.200500306 ID - Luk2006 ER - TY - JOUR AU - Tsai, Y. L. AU - Zhang, Y. AU - Tseng, C. C. AU - Stanciauskas, R. AU - Pinaud, F. AU - Lee, A. S. PY - 2015 DA - 2015// TI - Characterization and mechanism of stress-induced translocation of 78-kilodalton glucose-regulated protein (GRP78) to the cell surface JO - J Biol Chem VL - 290 UR - https://doi.org/10.1074/jbc.M114.618736 DO - 10.1074/jbc.M114.618736 ID - Tsai2015 ER - TY - JOUR AU - Mori, K. PY - 2000 DA - 2000// TI - Tripartite management of unfolded proteins in the endoplasmic reticulum JO - Cell VL - 101 UR - https://doi.org/10.1016/S0092-8674(00)80855-7 DO - 10.1016/S0092-8674(00)80855-7 ID - Mori2000 ER - TY - JOUR AU - Shu, C. W. AU - Sun, F. C. AU - Cho, J. H. AU - Lin, C. C. AU - Liu, P. F. AU - Chen, P. Y. PY - 2008 DA - 2008// TI - GRP78 and Raf-1 cooperatively confer resistance to endoplasmic reticulum stress-induced apoptosis JO - J Cell Physiol VL - 215 UR - https://doi.org/10.1002/jcp.21340 DO - 10.1002/jcp.21340 ID - Shu2008 ER - TY - JOUR AU - Lee, A. S. PY - 2014 DA - 2014// TI - Glucose-regulated proteins in cancer: molecular mechanisms and therapeutic potential JO - Nat Rev Cancer VL - 14 UR - https://doi.org/10.1038/nrc3701 DO - 10.1038/nrc3701 ID - Lee2014 ER - TY - JOUR AU - Zhang, Y. AU - Liu, R. AU - Ni, M. AU - Gill, P. AU - Lee, A. S. PY - 2010 DA - 2010// TI - Cell surface relocalization of the endoplasmic reticulum chaperone and unfolded protein response regulator GRP78/BiP JO - J Biol Chem VL - 285 UR - https://doi.org/10.1074/jbc.M109.087445 DO - 10.1074/jbc.M109.087445 ID - Zhang2010 ER - TY - JOUR AU - Liu, R. AU - Li, X. AU - Gao, W. AU - Zhou, Y. AU - Wey, S. AU - Mitra, S. K. PY - 2013 DA - 2013// TI - Monoclonal antibody against cell surface GRP78 as a novel agent in suppressing PI3K/AKT signaling, tumor growth, and metastasis JO - Clin Cancer Res VL - 19 UR - https://doi.org/10.1158/1078-0432.CCR-13-1106 DO - 10.1158/1078-0432.CCR-13-1106 ID - Liu2013 ER - TY - JOUR AU - Misra, U. K. AU - Pizzo, S. V. PY - 2012 DA - 2012// TI - Receptor-recognized alpha(2)-macroglobulin binds to cell surface-associated GRP78 and activates mTORC1 and mTORC2 signaling in prostate cancer cells JO - PLoS One VL - 7 UR - https://doi.org/10.1371/journal.pone.0051735 DO - 10.1371/journal.pone.0051735 ID - Misra2012 ER - TY - JOUR AU - Zhang, Y. AU - Tseng, C. C. AU - Tsai, Y. L. AU - Fu, X. AU - Schiff, R. AU - Lee, A. S. PY - 2013 DA - 2013// TI - Cancer cells resistant to therapy promote cell surface relocalization of GRP78 which complexes with PI3K and enhances PI(3,4,5)P3 production JO - PLoS One VL - 8 UR - https://doi.org/10.1371/journal.pone.0080071 DO - 10.1371/journal.pone.0080071 ID - Zhang2013 ER - TY - JOUR AU - Zhao, S. AU - Li, H. AU - Wang, Q. AU - Su, C. AU - Wang, G. AU - Song, H. PY - 2015 DA - 2015// TI - The role of c-Src in the invasion and metastasis of hepatocellular carcinoma cells induced by association of cell surface GRP78 with activated alpha2M JO - BMC Cancer VL - 15 UR - https://doi.org/10.1186/s12885-015-1401-z DO - 10.1186/s12885-015-1401-z ID - Zhao2015 ER - TY - JOUR AU - Misra, U. K. AU - Gonzalez-Gronow, M. AU - Gawdi, G. AU - Pizzo, S. V. PY - 2005 DA - 2005// TI - The role of MTJ-1 in cell surface translocation of GRP78, a receptor for alpha 2-macroglobulin-dependent signaling JO - J Immunol VL - 174 UR - https://doi.org/10.4049/jimmunol.174.4.2092 DO - 10.4049/jimmunol.174.4.2092 ID - Misra2005 ER - TY - JOUR AU - Burikhanov, R. AU - Zhao, Y. AU - Goswami, A. AU - Qiu, S. AU - Schwarze, S. R. AU - Rangnekar, V. M. PY - 2009 DA - 2009// TI - The tumor suppressor par-4 activates an extrinsic pathway for apoptosis JO - Cell VL - 138 UR - https://doi.org/10.1016/j.cell.2009.05.022 DO - 10.1016/j.cell.2009.05.022 ID - Burikhanov2009 ER - TY - JOUR AU - Al-Rawashdeh, F. Y. AU - Scriven, P. AU - Cameron, I. C. AU - Vergani, P. V. AU - Wyld, L. PY - 2010 DA - 2010// TI - Unfolded protein response activation contributes to chemoresistance in hepatocellular carcinoma JO - Eur J GastroenterolHepatol VL - 22 UR - https://doi.org/10.1097/MEG.0b013e3283378405 DO - 10.1097/MEG.0b013e3283378405 ID - Al-Rawashdeh2010 ER - TY - JOUR AU - Chiou, J. F. AU - Tai, C. J. AU - Huang, M. T. AU - Wei, P. L. AU - Wang, Y. H. AU - An, J. PY - 2010 DA - 2010// TI - Glucose-regulated protein 78 is a novel contributor to acquisition of resistance to sorafenib in hepatocellular carcinoma JO - Ann SurgOncol VL - 17 ID - Chiou2010 ER - TY - JOUR AU - Su, R. AU - Li, Z. AU - Li, H. AU - Song, H. AU - Bao, C. AU - Wei, J. PY - 2010 DA - 2010// TI - Grp78 promotes the invasion of hepatocellular carcinoma JO - BMC Cancer VL - 10 UR - https://doi.org/10.1186/1471-2407-10-20 DO - 10.1186/1471-2407-10-20 ID - Su2010 ER -