Table 5 Univariate and multivariate Cox regression analyses for cause-specific survival and overall survival (n = 72)
From: Clinical outcomes of transoral videolaryngoscopic surgery for hypopharyngeal and supraglottic cancer
Variables | Cause-specific survival | Overall survival | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
No. | Univariate analysis | Multivariate analysis | Univariate analysis | Multivariate analysis | ||||||||||
HR | (95% CI) | P-values | HR | (95% CI) | P-values | HR | (95% CI) | P-values | HR | (95% CI) | P-values | |||
Age, y | ||||||||||||||
<70 | 45 | 1.00 | reference | 1.00 | reference | 1.00 | reference | 1.00 | reference | |||||
≧70 | 27 | 0.93 | (0.22-3.89) | 0.920 | 1.15 | (0.24-5.42) | 0.858 | 0.94 | (0.34-2.60) | 0.913 | 1.00 | (0.34-2.89) | 0.994 | |
Sex | ||||||||||||||
Men | 67 | 1.00 | 1.00 | 1.00 | reference | 1.00 | reference | |||||||
Women | 5 | not calculablea | − | not calculablea | − | 0.61 | (0.08-4.75) | 0.636 | 1.27 | (0.13-12.38) | 0.835 | |||
Tumor site | ||||||||||||||
HPC | 58 | 1.00 | reference | 1.00 | reference | 1.00 | reference | 1.00 | reference | |||||
SGC | 14 | 0.57 | (0.07-4.68) | 0.605 | 0.38 | (0.04-3.43) | 0.386 | 0.60 | (0.14-2.64) | 0.498 | 0.54 | (0.11-2.69) | 0.450 | |
T stage | ||||||||||||||
Tis + T1 | 32 | 1.00 | reference | 1.00 | reference | 1.00 | reference | 1.00 | reference | |||||
T2-3 | 40 | 2.69 | (0.54-13.34) | 0.227 | 0.68 | (0.09-5.24) | 0.714 | 1.58 | (0.57-4.35) | 0.380 | 1.27 | (0.29-5.54) | 0.749 | |
N stage | ||||||||||||||
N0-1 | 48 | 1.00 | reference | 1.00 | reference | 1.00 | reference | 1.00 | reference | |||||
N2-3 | 24 | 15.45 | (1.90-125.69) | 0.010* | 25.51 | (2.29-284.17) | 0.008* | 2.94 | (1.09-7.90) | 0.032* | 4.90 | (1.26-19.08) | 0.022* | |
Multiple cancer | ||||||||||||||
No | 18 | 1.00 | reference | 1.00 | reference | 1.00 | reference | 1.00 | reference | |||||
Yes | 54 | 1.08 | (0.22-5.36) | 0.923 | 2.63 | (0.45-15.20) | 0.281 | 1.21 | (0.39-3.82) | 0.742 | 1.74 | (0.47-6.41) | 0.405 | |
Previous RT | ||||||||||||||
No | 60 | 1.00 | reference | 1.00 | 1.00 | reference | 1.00 | reference | ||||||
Yes | 12 | 0.68 | (0.08-5.52) | 0.717 | not calculableb | − | 1.09 | (0.31-3.83) | 0.894 | 2.23 | (0.34-14.86) | 0.406 | ||