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Table 4 Correlations between the overall survival and clinicopathological factors

From: The peripheral monocyte count is associated with the density of tumor-associated macrophages in the tumor microenvironment of colorectal cancer: a retrospective study

 

Univariate analysis

Multivariate analysis

 

HR

95% CI

P-value

HR

95% CI

P-value

Age (≥70 years vs. <70 years)

2.366

1.058–5.289

0.036

3.355

1.373–8.200

0.008

Gender (Male vs. Female)

1.250

0.565–2.765

0.582

   

Tumor depth (T4 vs. T1–3)

1.387

0.616–3.124

0.430

   

Histological type (Poorly, Mucinous vs. Well, Moderately)

1.660

0.495–5.573

0.412

   

Lymphatic involvement (Positive vs. Negative)

2.461

0.733–8.258

0.145

   

Venous involvement (Positive vs. Negative)

2.987

1.306–6.831

0.010

3.911

1.540–9.936

0.004

Lymph node metastasis (Positive vs. Negative)

2.641

1.135–6.148

0.024

1.729

0.699–4.273

0.236

CEA (>5 ng/ml vs. ≤5 ng/ml)

2.563

1.149–5.717

0.021

1.258

0.513–3.085

0.616

CA19–9 (>37 U/ml vs. ≤37 U/ml)

3.117

1.226–7.928

0.017

2.127

0.720–6.281

0.172

TAM (High vs. Low)

2.841

1.128–7.152

0.027

4.123

1.464–11.610

0.007

  1. HR hazard ratio, CI confidence interval, TAMs tumor-associated macrophages, CEA carcinoembryonic antigen, CA19–9 carbohydrate antigen 19–9