Table 2 DNA copy number of BCL2 family genes in parental cell lines and venetoclax-resistant populations. Key changes are highlighted in bold

BCL2

0.46

0.46

6.00

7.79

3.01

3.19

14.86

7.08

2.05

1.97

6.07

1.34

5.99

5.61

BCL2L1

2.08

2.27

2.17

9.16

2.08

2.03

2.09

2.14

2.06

2.05

1.93

1.99

1.83

1.85

MCL1

2.07

3.21

2.18

5.12

2.11

2.04

9.99

11.25

2.16

2.10

2.99

1.96

2.39

2.40

BCL2A1

2.04

2.08

2.10

2.07

2.08

2.03

3.05

2.88

2.00

2.03

1.91

1.91

2.33

2.05

BCL2L2

2.06

2.15

2.11

2.10

2.08

2.05

2.08

2.10

2.18

2.14

1.95

1.99

1.30

1.29

BAX

2.09

2.22

2.18

2.00

2.17

2.04

3.12

2.92

2.17

2.18

2.06

1.99

2.48

2.43

BAK1

2.06

2.17

2.23

2.12

1.13

1.01

2.16

2.16

2.12

2.11

2.02

2.10

1.94

1.93

BID

2.07

2.23

2.30

2.18

2.21

2.08

2.18

2.05

2.24

2.20

2.04

2.11

1.98

2.13

BCL2L11

2.02

2.10

2.46

2.02

2.10

0.46

1.13

2.01

1.99

1.99

1.97

2.21

1.93

2.12

PMAIP1

1.99

1.55

3.07

2.26

3.12

3.15

18.25

9.50

2.05

1.97

3.76

1.26

6.22

5.61

BBC3

2.09

2.22

2.24

2.00

2.17

2.04

3.12

2.92

2.17

2.18

2.06

1.99

2.41

2.43

BAD

2.01

2.11

2.36

2.18

2.07

2.05

2.11

2.07

2.12

2.12

2.05

2.00

1.86

1.60