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Table 2 Univariate and multivariate analysis of prognostic factors in the development cohort (n = 260)

From: An objective nodal staging system for breast cancer patients undergoing neoadjuvant systemic treatment

 

Univariate

Multivariate

P

HR

95% CI for HR

P

HR

95% CI for HR

Age

0.643

0.995

0.973

1.017

    

Tumor size

0.027

1.094

1.010

1.184

0.176

1.059

0.975

1.151

Axillary LN (1 cm)

0.006

1.097

1.028

1.172

0.051

1.072

1.000

1.149

High HG

0.001

2.226

1.377

3.598

0.014

1.934

1.146

3.266

HRc negative

0.005

1.841

1.204

2.815

    

HER2 positive

0.608

1.132

0.706

1.814

    

Subtypea

0.072

   

0.354

   

HRc+/HER2+

0.493

0.765

0.357

1.642

0.228

0.617

0.282

1.352

HRc−/HER2+

0.043

1.857

1.050

3.381

0.226

1.469

0.788

2.737

HRc−/HER2-

0.036

1.717

1.035

2.847

0.468

1.222

0.711

2.103

Ki67 ≥ 10%

0.322

1.240

0.810

1.898

    
  1. P values are derived from univariate or multivariate Cox proportional hazard models
  2. HR hazard ratio; CI confidence interval; LN lymph node; HG histologic grade; HRc hormone receptor; HER2 human epidermal growth factor receptor 2
  3. aHRc+/HER2- cases were used as reference group