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Table 2 The frequencies of MBL2 codon 54 and IL-8 -251 genotypes in the control and disease groups

From: Combination of Helicobacter pylori infection and the interleukin 8 –251 T > A polymorphism, but not the mannose-binding lectin 2 codon 54 G > A polymorphism, might be a risk factor of gastric cancer

Genotype

Control

n = 176 (%)

Hp (+)

NAG

n = 108 (%)

Hp (+)

Mild AG

n = 52 (%)

Hp (+)

Severe AG

n = 61 (%)

Hp (−)

DU

n = 7 (%)

Hp (+)

DU

n = 168 (%)

Hp (−)

GC

n = 76 (%)

Hp (+)

GC

n = 207 (%)

MBL2 codon 54

G/G (wild type)

103 (58.52)

65 (60.19)

29 (55.77)

32 (52.46)

4 (57.14)

95 (56.55)

41 (53.95)

129 (62.32)

G/A(heterozygote)

63 (35.80)

37 (34.26)

22 (43.31)

27 (44.26)

3 (42.86)

69 (41.07)

29 (32.37)

67 (32.37)

A/A (mutant)

10 (5.68)

6 (5.56)

1 (1.92)

2 (3.28)

0 (0.00)

4 (2.38)

6 (5.31)

11 (5.31)

G/A + A/A (A carrier)

73 (41.48)

43 (39.81)

23 (44.23)

29 (47.54)

4 (57.14)

73 (43.45)

35 (46.05)

78 (37.68)

IL-8 -251

T/T (wild type)

70 (39.77)

52 (48.15)

20 (38.46)

15 (24.59)

3 (42.86)

81 (48.21)

23 (30.26)

58 (28.02)

T/A (heterozygote)

89 (50.57)

49 (45.37)

27 (51.92)

37 (60.66)

3 (42.86)

73 (43.45)

46 (60.53)

122 (58.94)

A/A (mutant)

17 (9.66)

7 (6,48)

5 (9.62)

9 (16.75)

1 (14.29)

14 (8.33)

7 (9.21)

27 (13.04)

T/A + A/A (A carrier)

106 (60.23)

56 (51.85)

32 (61.54)

46 (75.41)

4 (57.14)

87 (51.79)

53 (69.74)

149 (71.99)

  1. The frequencies of MBL2 codon 54 and IL-8 -251 genotypes were not significantly different between the control and disease groups