TY - JOUR AU - Chang, Young Woon AU - Oh, Chi Hyuk AU - Kim, Jung-Wook AU - Lee, Jae Won AU - Park, Mi Ju AU - Shim, Jae-Jun AU - Lee, Chang Kyun AU - Jang, Jae-Young AU - Dong, Seok Ho AU - Kim, Hyo Jong AU - Kim, Sung Soo AU - Kim, Byung-Ho PY - 2017 DA - 2017/05/30 TI - Combination of Helicobacter pylori infection and the interleukin 8 –251 T > A polymorphism, but not the mannose-binding lectin 2 codon 54 G > A polymorphism, might be a risk factor of gastric cancer JO - BMC Cancer SP - 388 VL - 17 IS - 1 AB - Mannose-binding lectin (MBL) acts in the innate immune response to Helicobacter pylori. Interleukin 8 (IL-8) is a potent cytokine produced by gastric epithelial cells in response to H. pylori. We aimed to investigate whether polymorphisms in MBL2 and IL-8 influence susceptibility to H. pylori infection, and the associations of these polymorphisms with the risk of gastroduodenal diseases in a Korean population. SN - 1471-2407 UR - https://doi.org/10.1186/s12885-017-3378-2 DO - 10.1186/s12885-017-3378-2 ID - Chang2017 ER -