Fig. 4
From: GABPA predicts prognosis and inhibits metastasis of hepatocellular carcinoma
GABPA induced HCC cell migration partly by modulating E-cadherin. a GABPA overexpression reduced migration potency (lane 1 vs. 3), whereas addition of E-cadherin antibody to block E-cadherin function partially restored HCC cell migration capacity (lane 3 vs. 4). Lane 2 was used as a positive control. b Migration assays showed that GABPA overexpression-induced reduction of migration potency was partially impaired by knockdown of E-cadherin expression. c GABPA did not bind directly to the E-cadherin promoter (*P < 0.05, **P < 0.01)