Skip to main content

Table 2 Univariate and multivariate analyses of prognostic factors for overall survival and progression-free survival

From: Preoperative Prognostic Nutritional Index is a Significant Predictor of Survival with Bladder Cancer after Radical Cystectomy: a retrospective study

Variable Univariate Multivariate
P value HR (95% CI) P Value
Overall survival    
 Age (>65 vs. ≤65) <0.001 1.615 (1.116–2.337) 0.011
 Gender (male vs. female) 0.264   
 Histology type (NUC vs. UC) 0.363   
 Pathological grade (3 vs. 2) <0.001   
 pT (pT2 or greater vs. pT1) <0.001 2.796 (1.700–4.598) <0.001
 pN status (positive vs. negative) <0.001 1.682 (1.141–2.480) 0.009
 Smoking history 0.937   
 Hypertension 0.480   
 Diabetes Mellitus 0.534   
 Heart disease 0.018   
 Cerebrovascular disease 0.032   
 ASA grade (3&4 vs. 1&2) <0.001 1.641 (1.113–2.418) 0.012
 Hypoalbuminemia <0.001   
 Anemia <0.001   
 Postoperative complications 0.003 1.607 (1.076–2.400) 0.020
 PNI (low vs. high) <0.001 1.668 (1.147–2.425) 0.007
 PLR (high vs. low) <0.001   
 NLR (high vs. low) <0.001 1.416 (1.094–2.016) 0.014
 LMR (low vs. high) <0.001   
Progression-free survival    
 Age (>65 vs. ≤65) <0.001   
 Gender (male vs. female) 0.304   
 Histology type (NUC vs. UC) 0.683   
 Pathological grade (3 vs. 2) <0.001   
 pT (pT2 or greater vs. pT1) <0.001 2.560 (1.677–3.906) <0.001
 pN status (positive vs. negative) <0.001 1.871 (1.306–2.680) 0.001
 Smoking history 0.952   
 Hypertension 0.604   
 Diabetes Mellitus 0.681   
 Heart disease 0.012   
 Cerebrovascular disease 0.033   
 ASA grade (3&4 vs. 1&2) <0.001 1.561 (1.086–2.243) 0.016
 Hypoalbuminemia <0.001   
 Anemia <0.001   
 Postoperative complications 0.004   
 PNI (low vs. high) <0.001 1.680 (1.092–2.005) 0.011
 PLR (high vs. low) <0.001   
 NLR (high vs. low) <0.001 1.550 (1.140–2.388) 0.008
 LMR (low vs. high) <0.001   
  1. UC urothelial carcinoma, NUC non-urothelial carcinoma, ASA American Society of Anesthesiologists, PNI prognostic nutritional index, NLR neutrophil-lymphocyte ratio, PLR platelet-lymphocyte ratio, LMR lymphocyte-monocyte ratio
  2. Significant values are in bold