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Table 3 Univariate and multivariate statistical analysis of overall survival
| Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|
| Factor | p | OR | 95% CI | p | OR | 95% CI |
| Gender (male vs. female) | 0,281 | 0,67 | 0,32–1,39 | |||
| Age (years) (<54 vs. ≥55) | 0,001 | 8,92 | 3,63–21,92 | 0,002 | 5,92 | 1,95–17,96 |
| Disease duration (years) (<5 vs. ≥5) | 0,421 | 1,31 | 0,68–2,53 | |||
| T stadium (T1 and T2 vs. T3 and T4) | 0,001 | 4,47 | 2,03–9,82 | 0,002 | 4,31 | 1,67–11,09 |
| N stadium (N0 and Nx vs. N1a and N1b) | 0,601 | 1,46 | 0,35–6,11 | |||
| Tumor type (minimally vs. widely invasive) | 0,044 | 1,96 | 1,01–3,79 | |||
| Tumor size (mm) (≤39 vs. >40) | 0,004 | 4,19 | 1,57–11,19 | |||
| Capsular invasion (positive vs. no or minimal) | 0,38 | 1,42 | 0,65–3,11 | |||
| Vascular invasion (positive vs. no or minimal) | 0,287 | 0,61 | 0,25–1,50 | |||
| Number of tumor focuses (one vs. multicentric) | 0,104 | 1,84 | 0,88–3,85 | |||
| Affection of both lobes (yes vs. no) | 0,004 | 2,93 | 1,4–6,12 | 0,005 | 3,29 | 1,42–7,62 |
| Regional tumor infiltration (yes vs. no) | 0,003 | 0,35 | 0,17–0,7 | |||
| Primary procedure (total thyroidectomy vs. less than total) | 0,65 | 1,18 | 0,56–2,48 | |||
| Total thyroidectomy after lobectomy (yes vs. no) | 0,19 | 0,44 | 0,12–1,53 | |||
| Type of procedure overall (total thyroidectomy vs. less than total) | 0,836 | 0,92 | 0,4–2,09 | |||
| Reoperation due to relapse (yes vs. no) | 0,035 | 0,407 | 0,17–0,94 | 0,016 | 0,3 | 0,11–0,79 |
| Surgeon’s experience (years) (<10 vs. 10+) | 0,25 | 0,66 | 0,32–1,33 | |||
| Radioiodine ablation (yes vs. no) | 0,43 | 1,88 | 0,39–9,08 | |||
| Diabetes mellitus (yes vs. no) | 0,3 | 0,53 | 0,16–1,77 | |||
| Hypertension (yes vs. no) | 0,002 | 0,32 | 0,16–0,65 | |||
| Other malignancies (yes vs. no) | 0,275 | 0,55 | 0,19–1,59 | |||
| Thyroglobulin (ng/mL) (<300 vs. >300) | 0,925 | 1,11 | 0,11–10,9 | |||
