Fig. 4

Immunohistochemical evaluation of ERG expression in 239 PCa specimens. a, Representative immunohistochemistry images for ERG with low expression (ERG-negative, top panels) and high expression (ERG-positive, bottom panels) in PCa tissue array samples (magnification, ×20); b, the first quartile value of IGF-1R RQ was separately calculated for the ERG–negative (top) and ERG-positive (bottom) groups, and the samples were classified as high-expression (H) and low-expression (L). Time scale refers to months from diagnosis. Black lines indicate high-expressing patients. BPFS, biochemical progression-free survival; PFS, clinical progression-free survival. The number of patients at risk in the high- (top) and low-expression (bottom) samples is listed above each time interval