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Fig. 3 | BMC Cancer

Fig. 3

From: The unique C- and N-terminal sequences of Metallothionein isoform 3 mediate growth inhibition and Vectorial active transport in MCF-7 cells

Fig. 3

Dendogram showing the relatedness of global gene expression patterns among MCF-7 cells stably expressing each metallothionein construct. Constructs contain either wild-type MT3, MT3 with the N-terminal domain mutated (MT3ΔNT), the C-terminal domain mutated (MT3ΔCT), wild type MT1E, MT1E containing the N-terminal domain of MT3 (MT1E-NT), MT1E with the C-terminal domain of MT3 (MT1E-CT), or the blank vector (pcDNA 6.2/V5). The effect of each construct was assessed in triplicate with each triplicate shown individually as either (a), (b), or (c). The clustering was assessed by overlap hierarchical clustering

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