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Fig. 9 | BMC Cancer

Fig. 9

From: Role of peptidylarginine deiminase 2 (PAD2) in mammary carcinoma cell migration

Fig. 9

Mammary gland development in diestrus 8 week old female wild type and MMTV-PAD2 mice. a Graph quantifying number of branches/field in mammary glands from 8 week old diestrus wild type and MMTV-PAD2 female mice (n = 3). Representative whole mount images (20×) of mammary gland development in wild type and PAD2 overexpressing mice. Following isolation, mammary fat pads were stained with carmine-alum for visualization. b Images of formalin-fixed-paraffin embedded mammary gland tissue sections following H&E staining at 5× (low magnification) and 20× (high magnification). Note the normal appearance of acini in WT mice showing typical epithelial layer and lumen. In MMTV-PAD2 mice the acini are less organized with apparent infiltration of epithelial cells into the lumen

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