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Fig. 2 | BMC Cancer

Fig. 2

From: Role of peptidylarginine deiminase 2 (PAD2) in mammary carcinoma cell migration

Fig. 2

Single cell migration is impaired in PAD2 depleted MCF10DCIS.com cells. a Images of MCF10DCIS.com scrambled-shRNA and PADI2-shRNA cells taken at times 0, 3, 6, 9, 12, and 15 h at the same location using a wide-field microscope with a built-in incubation chamber. The arrow indicates the directional movement of the cells. Scale bar = 50 μm. b Graphical representation of the movement of individual cells (n = 20) of scrambled-shRNA and PADI2-shRNA cells in culture. The line shows the trails of the cell movement and the black circle shows the final location of the cells. The point of origin is shown as a white dot. Graphs were generated using Tracking Tool™ Pro v2.0. c Graph depicts accumulated distance travelled and (d) average velocity by single scrambled-shRNA and PADI2-shRNA cells

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