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Fig. 5 | BMC Cancer

Fig. 5

From: JS-K, a nitric oxide pro-drug, regulates growth and apoptosis through the ubiquitin-proteasome pathway in prostate cancer cells

Fig. 5

C4-2 and LNCaP cells were incubated for three periods (3, 6 and 9 h) with 5 μM JS-K; a Western blotting was performed to access the influence of JS-K on AR and Siah2 protein levels; b Co-IP was performed to access the influence of JS-K on combination between AR and Siah2 in C4-2 and LNCaP cells incubated for 9 h with 5 μM JS-K; c Co-IP was performed to access the influence of JS-K on combination of Ubiquitin and AR in C4-2 and LNCaP cells incubated for 9 h with 5 μM JS-K while maybe JS-K inhibited polyubiquitin of AR mediated by ubiquitin E3 ligase Siah2; All the IP were used in the input and at least three different experiments were performed

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BMC Cancer

ISSN: 1471-2407

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