Fig. 1
The inhibitory effect of JS-K on proliferation of C4-2 cells (a) and LNCaP (b). C4-2 and LNCaP cells were treated with indicated concentration of JS-K (5 μM) for three periods (12, 24 and 48 h). The viability of cells was measured by CCK-8 assay. (c) The IC50 of JS-K for LNCaP and C4-2 cell lines were tested, while the cells were treated with JS-K (0, 1, 2, 5, 10 and 20 μM) for 48 hours. Each assay was performed in triplicate. Results are mean ± SD of three different experiments. Single asterisks (*) indicate a significant difference (P < 0.05) and triple asterisks (***) indicates an extremely significant difference (P < 0.001)