Fig. 1

Morphology of parent OVA-BS4 (magnification 200X) (a) and OVA-BS4 spheroids (magnification 100X) (b). Parent OVA-BS4 were cultured in RPMI 10%FBS in adhesion condition, whereas OVA-BS4 spheroids were obtained from parent OVA-BS4 cell line under selective culture condition (serum-free DMEM/F12 medium supplemented with 5 μg/ml human insulin, 20 ng/ml EGF, 10 ng/ml bFGF, and B27 Supplement, in ultra low-attachment plates)