Fig. 3
From: Identification of endonuclease domain-containing 1 as a novel tumor suppressor in prostate cancer
ENDOD1 suppresses the proliferation of prostate cancer cells. a-b Western blot analysis confirmed ENDOD1 overexpression in DU145 (a) and downregulation in LNCaP (b) cells. c-d MTT assays demonstrated inhibitory effect of ENDOD1 on cell proliferation of PCa cells. ENDOD1 overexpression significantly suppressed proliferation of DU145 cells (c), whereas siRNA-induced downregulation of ENDON1promoted proliferation of LNCaP cells (d). Cell growth curves were plotted according to absorbance at 490Â nm. *PÂ <Â 0.05