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Table 4 Multivariate Cox hazard ratio models for the impact of low cholesterol on cancer-specific and overall survival after surgical treatment of metastatic renal cell carcinoma

From: Preoperative cholesterol level as a new independent predictive factor of survival in patients with metastatic renal cell carcinoma treated with cyto-reductive nephrectomy

 

Cancer-specific survival

Overall survival

HR

95% CI of HR

p-value

HR

95% CI of HR

p-value

Entire cohorts

2.162

1.221–3.829

0.008

2.013

1.206–3.361

0.007

Subgroups according to the tumor histology

 Clear cell histology

2.312

1.274–4.193

0.006

2.204

1.279–3.799

0.004

 Other histology

0.767

0.076–7.771

0.822

0.285

0.043–1.879

0.192

Subgroups according to the Heng’s model

 Favorable risk

1.556

0.487–4.967

0.455

1.767

0.602–5.185

0.300

 Intermediate

1.809

0.907–3.611

0.093

1.583

0.851–2.947

0.147

 Poor

1.538

0.339–6.972

0.577

1.735

0.406–7.416

0.457

  1. Multivariate analyses were adjusted for age, body mass index, Heng’s risk group, preoperative albumin and cholesterol level. HR hazard ratio, CI confidence interval