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Table 3 Multivariate Cox regression model adjusted for possible predictors estimating cancer-specific and overall survival in 244 patients treated with cyto-reductive nephrectomy for metastatic renal cell carcinoma

From: Preoperative cholesterol level as a new independent predictive factor of survival in patients with metastatic renal cell carcinoma treated with cyto-reductive nephrectomy

  Cancer-specific survival Overall survival
HR 95% CI of HR p value HR 95% CI of HR p value
Age 1.002 0.983–1.021 0.865 1.003 0.986–1.021 0.713
BMI (kg/m 2) Reference (< 20) Reference (< 20)
 20–25 0.792 0.459–1.369 0.404 0.805 0.485–1.336 0.402
  ≥ 25 0.443 0.202–0.924 0.030 0.466 0.232–0.936 0.032
Albumin (g/dL) Reference (< 3.5) Reference (< 3.5)
 3.5–4.3 0.776 0.440–1.370 0.382 0.716 0.426–1.204 0.208
  ≥ 4.3 0.784 0.399–1.544 0.482 0.713 0.383–1.328 0.287
Heng’s criteria Reference (Low risk) Reference (Low risk)
 Intermediate risk 1.095 0.623–1.926 0.752 1.033 0.619–1.725 0.902
 High risk 1.185 0.550–2.553 0.664 1.132 0.565–2.270 0.727
 Cholesterol level (cat.) 2.162 1.221–3.829 0.008 2.013 1.206–3.361 0.007
Age 1.002 0.983–1.021 0.830 1.003 0.986–1.021 0.701
BMI (kg/m 2) Reference (< 20) Reference (< 20)
 20–25 0.827 0.479–1.430 0.497 0.857 0.517–1.420 0.549
  ≥ 25 0.462 0.214–0.997 0.049 0.503 0.249–1.017 0.056
Albumin (g/dL) Reference (< 3.5) Reference (< 3.5)
 3.5–4.3 0.882 0.498–1.561 0.665 0.789 0.468–1.327 0.371
  ≥ 4.3 0.892 0.437–1.821 0.753 0.769 0.401–1.473 0.428
Heng’s criteria Reference (Low risk) Reference (Low risk)
 Intermediate 1.060 0.601–1.870 0.840 1.024 0.613–1.712 0.927
 High risk 1.235 0.576–2.649 0.588 1.193 0.596–2.389 0.618
 Cholesterol level (con.) 0.993 0.987–0.999 0.032 0.995 0.989–1.000 0.063
  1. HR hazard ratio, CI confidence interval, BMI body mass index, con. Continuous variable, cat. Categorical variable