Fig. 3

Representative computed tomography images from the study arm (case 4 in Table 4) treated with the miriplatin-TOCE/DDP-H-HAIC combination therapy. Pre-TX arterial: Multiple nodules were spread in both lobes and enhanced in the late arterial phase of a dynamic computed tomography study performed prior to the treatment (black and white arrowheads). post-Tx pre-contrast: These nodules were detected as high density spots of lipiodol without an injection of contrast medium three months after the eighth session of combination therapy (black arrowheads). post-Tx arterial: The high density spots were scarcely enhanced and markedly reduced in size (black arrowheads). One nodule, which is indicated by the white arrowhead in the pre-Tx arterial column, could not be detected at post-Tx either in the pre-contrast or in the arterial phase