Skip to main content

Table 3 Relationships between clinicopathological parameters of OSCC and densities of tumor infiltrating immune cells

From: Prognostic significance of tumor infiltrating immune cells in oral squamous cell carcinoma

Factors CD8 CD4 T-bet CD68 CD57
Low High P-Value Low High P-Value Low High P-Value Low High P-Value Low High P-Value
Age
  < 60 18 17 0.981 17 18 0.821 21 14 0.046* 21 14 0.238 23 12 0.137
  ≥ 60 22 21   22 21   16 27   20 23   21 22
Gender
 Male 31 27 0.517 29 29 1 28 30 0.802 30 28 0.802 32 26 0.709
 Female 9 11   10 10   9 11   11 9   12 8
Smoking
 Yes 27 21 0.27 25 23 0.644 23 25 0.915 24 24 0.569 28 20 0.667
 No 13 17   14 16   14 16   17 13   16 14
Drinking
 Yes 27 15 0.014* 23 19 0.367 21 21 0.626 24 18 0.385 26 16 0.294
 No 13 23   16 20   16 20   17 19   18 18
Differentiation
 Well 26 31 0.101 31 26 0.205 27 30 0.984 28 29 0.319 32 25 0.937
 Moderate or Poor 14 7   8 13   10 11   13 8   12 9
T stage
 T1 and T2 29 29 0.702 29 29 1 26 32 0.435 28 30 0.199 30 28 0.158
 T3 and T4 11 9   10 10   11 9   13 7   14 6
N stage
 N0 20 28 0.033* 23 25 0.644 22 26 0.722 24 24 0.569 21 27 0.005*
 N1-N3 20 10   16 14   15 15   17 13   23 7
Clinical stage
 I and II 16 20 0.266 18 18 1 15 21 0.348 16 20 0.186 15 21 0.016*
 III and IV 24 18   21 21   22 20   25 17   29 13
  1. *P values showing statistically significance were indicated by*