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Table 3 Relationships between clinicopathological parameters of OSCC and densities of tumor infiltrating immune cells

From: Prognostic significance of tumor infiltrating immune cells in oral squamous cell carcinoma

Factors

CD8

CD4

T-bet

CD68

CD57

Low

High

P-Value

Low

High

P-Value

Low

High

P-Value

Low

High

P-Value

Low

High

P-Value

Age

  < 60

18

17

0.981

17

18

0.821

21

14

0.046*

21

14

0.238

23

12

0.137

  ≥ 60

22

21

 

22

21

 

16

27

 

20

23

 

21

22

Gender

 Male

31

27

0.517

29

29

1

28

30

0.802

30

28

0.802

32

26

0.709

 Female

9

11

 

10

10

 

9

11

 

11

9

 

12

8

Smoking

 Yes

27

21

0.27

25

23

0.644

23

25

0.915

24

24

0.569

28

20

0.667

 No

13

17

 

14

16

 

14

16

 

17

13

 

16

14

Drinking

 Yes

27

15

0.014*

23

19

0.367

21

21

0.626

24

18

0.385

26

16

0.294

 No

13

23

 

16

20

 

16

20

 

17

19

 

18

18

Differentiation

 Well

26

31

0.101

31

26

0.205

27

30

0.984

28

29

0.319

32

25

0.937

 Moderate or Poor

14

7

 

8

13

 

10

11

 

13

8

 

12

9

T stage

 T1 and T2

29

29

0.702

29

29

1

26

32

0.435

28

30

0.199

30

28

0.158

 T3 and T4

11

9

 

10

10

 

11

9

 

13

7

 

14

6

N stage

 N0

20

28

0.033*

23

25

0.644

22

26

0.722

24

24

0.569

21

27

0.005*

 N1-N3

20

10

 

16

14

 

15

15

 

17

13

 

23

7

Clinical stage

 I and II

16

20

0.266

18

18

1

15

21

0.348

16

20

0.186

15

21

0.016*

 III and IV

24

18

 

21

21

 

22

20

 

25

17

 

29

13

  1. *P values showing statistically significance were indicated by*