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Fig. 1 | BMC Cancer

Fig. 1

From: MDA-MET-conditioned-medium augments the chemoattractant-dependent migration of MDA-MET cells towards hFOB-conditioned medium and increases collagenase activity

Fig. 1

Effects of conditioned medium on hFOB cell secreted medium attraction of MDA-MET cells. Left Panel) hFOBCM[MDA-METCM] attracts a greater number of MDA-MET cells than either hFOBCM[hFOBCM] or hFOBCM[HTERT-HME1CM]. Conditioned medium was removed from confluent hFOB cells which had been exposed over a 24 h period to conditioned medium from confluent cells of the following lines: MDA-MET(METCM), hFOB (hFOBCM) HTERT-HME1 (HTERTCM) or un-conditioned medium. The number of migrating cells is directly proportional to fluorescence and represented as fluorescence on y axis n = 18–24, * p < 0.05 vs hFOBCM[METCM]; # p < 0.05 vs all other groups. Right Panel) There is no difference between the number of cells attracted to HBMECCM[MDA-METCM] compared to the number attracted to HBMECCM[HTERT-HME1CM] or HBMEC[HBMECCM]. Conditioned medium was removed from confluent HBMEC cells which had been exposed over a 24 h period to conditioned medium from confluent cells of the following lines: MDA-MET(METCM), HBMEC(HBMECCM) HTERT-HME1 (HTERTCM) or un-conditioned medium. The number of cells is directly proportional to fluorescence and represented as fluorescence on y axis n = 9

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BMC Cancer

ISSN: 1471-2407

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