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Table 4 Results of the gene-based association test from VEGAS (only genes with P Gene < 0.05 or best SNP P per allele < 0.05 are shown)

From: Investigation of DNA repair-related SNPs underlying susceptibility to papillary thyroid carcinoma reveals MGMT as a novel candidate gene in Belarusian children exposed to radiation

Chr Gene Start Stop Number of tested SNPs Number of simulations Test P Gene Best SNP P per allele
10 MGMT 131,215,453 131,615,783 4 1e + 05 13.93 0.008 rs2296675 0.0006
13 ERCC5 103,448,190 103,578,351 2 1e + 06 9.39 0.01 rs1047768 0.02
20 PCNA 5,045,598 5,157,268 3 1e + 05 9.30 0.05 rs17349 0.03
7 PMS2 5,962,869 6,098,737 4 1000 8.70 0.09 rs3735295 0.04
1 PARP1 226,498,391 226,645,801 5 1000 11.05 0.11 rs747659 0.03
3 OGG1 9,741,627 9,858,353 2 1000 4.30 0.13 rs125701 0.05
2 XRCC5 216,924,019 217,121,016 4 1000 7.79 0.13 rs1051685 0.008
  1. Chr chromosome, Start coordinate of the 5′ end of the gene on the chromosome, Stop coordinate of the 3′ end of the gene on the chromosome.