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Table 4 Univariate and multivariate analysis of factors predictive of postoperative ipsilateral plural effusion and drainage after diaphragm surgery

From: Diaphragmatic Surgery and Related Complications In Primary Cytoreduction for Advanced Ovarian, Tubal, and Peritoneal Carcinoma

Univariate
 Parameters Pleural effusions Pleural drainage
P value P value
  Age (>55 years old) 0.908 0.080
  Tumor stage (IV vs. IIIC) <0.001 0.009
  Preoperative pleural effusion 0.215 0.831
  Ascites >2000 mL 0.558 0.878
  CA-125 > 1166 U/mL 0.729 0.482
  Albumin <3.9 g/dL 0.568 0.815
  Diaphragmatic surgery (DFTR vs. DP) <0.001 <0.001
  Perforation into pleural cavity 0.996 0.996
  TDDE 0997 <0.001
  Pleural nodule biopsy 0.998 0.995
  Operating time > 180 min <0.001 0.015
  Estimated blood loss >900 mL 0.249 0.442
  Intraoperative blood transfusion >4.0 units 0.016 0.719
Multivariate
 Parameters Pleural effusions Pleural drainage
HR (95% CI) P value HR (95% CI) P value
  Tumor stage (IV vs. IIIC) 17.2 (4.5–66.7) <0.001 4.5 (0.8–25.7) 0.086
  Diaphragmatic surgery (DFTR vs. DP) 4.9 (1.2–19.9) 0.028 5.9 (1.5–23.6) 0.011
  TDDE / / 28.3 (4.9–160.8) <0.001
  Operating time > 180 min 15.4 (4.3–55.5) <0.001 2.2 (0.6–8.6) 0.242
  Intraoperative blood transfusion >4.0 units 0.7 (0.2–2.3) 0.581 / /
  1. Note: Values in bold are statistically significant.
  2. Abbreviations: CA-125 cancer antigen 125, DP diaphragm peritonectomy, DFTR diaphragm full-thickness resection, TDDE trans-diaphragmatic thoracic exploration, HR hazard ratio, CI confidence interval.