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Table 3 Perioperative surgical complications based on type of diaphragm surgery

From: Diaphragmatic Surgery and Related Complications In Primary Cytoreduction for Advanced Ovarian, Tubal, and Peritoneal Carcinoma

  Cohort
(n = 150)
DP
(n = 124)
DFTR
(n = 26)
P
All complications
 Ipsilateral pleural effusion (%) 50 (33.3%) 32 (25.8%) 18 (69.2%) <0.001
 Ipsilateral pneumothorax (%) 11 (7.3%) 8 (6.5%) 3 (11.5%) 0.623
 Pulmonary embolism (%) 2 (1.3%) 2 (1.6%) 0 1.000
 Pneumonia (%) 23 (15.3%) 20 (16.1%) 3 (11.5%) 0.771
 Right hepatic vein rupture 1 (0.6%) 0 1 (3.8%) 1.000
 Sub-diaphragmatic abscess 1 (0.6%) 1 (0.8%) 0 1.000
 Postoperative bleeding (%) 1 (0.6%) 1 (0.8%) 0 1.000
 Bowel obstruction (%) 10 (6.7%) 9 (7.3%) 1 (3.8%) 0.825
 Pancreatic leak 1 (0.6%) 1 (0.8%) 0 1.000
 Intestinal perforation 1 (0.6%) 1 (0.8%) 0 1.000
 Heart arrhythmia 1 (0.6%) 1 (0.8%) 0 1.000
 Wound infection/dehiscence 5 (3.3%) 3 (2.4%) 2 (7.7%) 0.447
 Vaginal cuff infection 1 (0.6%) 1 (0.8%) 0 1.000
 Urinary tract infection 1 (0.8%) 1 (0.8%) 0 1.000
MSKCC grading
 Grade 1–2 (%) 82 (54.7%) 66 (53.2%) 16 (61.5%) 0.010
 Grade 3–5 (%) 27 (18.0%) 15 (12.1%) 12 (46.2%)
Grade 3–5 complicationsa
 Symptomatic pleural effusion requiring drainage 21 (14.0%) 11 (8.9%) 10 (38.5%) <0.001
 Symptomatic pneumothorax requiring thoracostomy tube 1 (0.6%) 0 1 (3.8%) 1.000
 Right hepatic vein rupture requiring intra-operative repair and transfusion 1 (0.6%) 0 1 (3.8%) 1.000
 Bleeding requiring return to operating room 1 (0.6%) 1 (0.8%) 0 1.000
 Pancreatic leak requiring drainage 1 (0.6%) 1 (0.8%) 0 1.000
 Intestinal perforation requiring return to the operating room 1 (0.6%) 1 (0.8%) 0 1.000
 Wound dehiscence requiring delayed repair 1 (0.6%) 1 (0.8%) 0 1.000
  1. Abbreviations: DP diaphragm peritonectomy, DFTR diaphragm full-thickness resection, MSKCC Memorial Sloan Kettering Cancer Center
  2. Note:
  3. 1. Percentages are not additive as multiple procedures might be performed on the same patient.
  4. 2. Values in bold are statistically significant.
  5. aSevere complications leading to invasive radiologic intervention/re-operation/unplanned ICU admission (grade 3), chronic disability (grade 4), or death (grade 5).