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Table 2 Surgical procedures and outcomes based on type of diaphragm surgery

From: Diaphragmatic Surgery and Related Complications In Primary Cytoreduction for Advanced Ovarian, Tubal, and Peritoneal Carcinoma

 

Cohort

(n = 150)

DP

(n = 124)

DFTR

(n = 26)

P

Laterality of diaphragm lesions (%)

 Right

95 (63.3%)

78 (62.9%)

17 (65.4%)

0.811

 Left

1 (0.7%)

1 (0.8%)

0

 Bilateral

54 (36.0%)

45 (36.3%)

9 (34.6%)

Perforation into pleural cavity (%)

65 (43.3%)

39 (31.5%)

26 (100%)

<0.001

TDDE (%)

34 (22.7%)

21 (16.9%)

13 (50.0%)

<0.001

Pleural nodule biopsy performed (%)

21 (14.0%)

15 (12.1%)

6 (23.1%)

0.248

Prophylactic chest tube placement (%)

8 (5.3%)

5 (4.0%)

3 (11.5%)

0.285

Mesh utilization in diaphragm repair (%)

4 (2.7%)

0

4 (15.4%)

<0.001

Extended procedures performed (%)

 Small bowel resection

5 (3.3%)

5 (4.0%)

0

0.660

 Large bowel resection

48 (32.0%)

37 (29.8%)

11 (42.3%)

0.215

 Splenectomy

18 (12.0%)

14 (11.3%)

4 (15.4%)

0.801

 Partial pancreatectomy

5 (3.3%)

4 (3.2%)

1 (3.8%)

1.000

 Partial hepatic resection

4 (2.7%)

4 (3.2%)

0

0.796

 Resection of porta hepatis tumor

4 (2.7%)

3 (2.4%)

1 (3.8%)

1.000

 Cholecystectomy

1 (0.7%)

1 (0.8%)

0

1.000

 Stomia

15 (10.0%)

12 (9.7%)

3 (11.5%)

1.000

 Resection of the tumor on the liver surface

23 (15.3%)

20 (16.1%)

3 (11.5%)

0.771

 Resection of the tumor on the stomach surface

13 (8.7%)

10 8.1(%)

3 (11.5%)

0.850

 Resection of the tumor in the gallbladder fossa

6 (4.0%)

6 (4.8%)

0

0.552

Residual disease (%)

 Complete cytoreduction

53 (35.3%)

42 (33.9%)

11 (42.3%)

0.649

 Residual disease ≤1 cm

73 (48.7%)

61 (49.2%)

12 (46.2%)

Median operation time (range), minutes

180 (60–330)

180 (60–330)

195 (90–270)

0.576

Median EBL (range), mL

900 (100–5300)

900 (100–5300)

1000 (200–2200)

0.802

Intraoperative blood transfusion (%)

132 (88%)

109 (87.9%)

23 (88.5%)

0.937

Median transfusion amount (range), units

4.0 (1.0–15.0)

4.5 (1–15)

4 (2–13)

0.286

Planned intensive care unit stay (%)

46 (30.7%)

39 (30.6%)

8 (30.8%)

0.649

Median time interval from surgery to chemotherapy (range), days

14 (6–40)

14 (6–40)

14 (6–34)

0.272

  1. Note: Values in bold are statistically significant.
  2. Abbreviations: DP diaphragm peritonectomy, DFTR diaphragm full-thickness resection, TDDE trans-diaphragmatic thoracic exploration, EBL estimated blood loss