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Table 4 Sensitivity and specificity estimates for each cytokine as a diagnostic test for gastric cancer

From: Circulating blood levels of IL-6, IFN-γ, and IL-10 as potential diagnostic biomarkers in gastric cancer: a controlled study

IL-1β
 Sensitivity 0.76 0.68–0.85
 Specificity 0.43 0.34–0.53
 PPV 0.51 0.42–0.59
 NPV 0.70 0.61–0.82
IL-6
 Sensitivity 0.39 0.29–0.49
 Specificity 0.97 0.93–1.00
 PPV 0.90 0.80–0.99
 NPV 0.67 0.60–0.74
IFN-ү
 Sensitivity 0.71 0.63–0.78
 Specificity 0.53 0.44–0.62
 PPV 0.64 0.57–0.72
 NPV 0.60 0.51–0.70
IL-10
 Sensitivity 0.48 0.38–0.59
 Specificity 0.82 0.75–0.89
 PPV 0.67 0.56–0.79
 NPV 0.67 0.59–0.75
MCP-1
 Sensitivity 0.42 0.32–0.52
 Specificity 0.49 0.40–0.58
 PPV 0.39 0.29–0.49
 NPV 0.51 0.42–0.61
  1. PPV positive predictive value
  2. NPV negative predictive value