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Table 4 Sensitivity and specificity estimates for each cytokine as a diagnostic test for gastric cancer

From: Circulating blood levels of IL-6, IFN-γ, and IL-10 as potential diagnostic biomarkers in gastric cancer: a controlled study

IL-1β

 Sensitivity

0.76

0.68–0.85

 Specificity

0.43

0.34–0.53

 PPV

0.51

0.42–0.59

 NPV

0.70

0.61–0.82

IL-6

 Sensitivity

0.39

0.29–0.49

 Specificity

0.97

0.93–1.00

 PPV

0.90

0.80–0.99

 NPV

0.67

0.60–0.74

IFN-ү

 Sensitivity

0.71

0.63–0.78

 Specificity

0.53

0.44–0.62

 PPV

0.64

0.57–0.72

 NPV

0.60

0.51–0.70

IL-10

 Sensitivity

0.48

0.38–0.59

 Specificity

0.82

0.75–0.89

 PPV

0.67

0.56–0.79

 NPV

0.67

0.59–0.75

MCP-1

 Sensitivity

0.42

0.32–0.52

 Specificity

0.49

0.40–0.58

 PPV

0.39

0.29–0.49

 NPV

0.51

0.42–0.61

  1. PPV positive predictive value
  2. NPV negative predictive value