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Table 2 Frequency of cases and controls by clinicopathological factors

From: Presence of human papillomavirus DNA in breast cancer: a Spanish case-control study

  Number Cases n (%) Controls n (%) p-value
(p-value adjusting for age)
OR (CI 95%) AOR by Age (CI 95%)
Age (years) < 40 109 19 (7.6) 90 (48.4) <0.001 1
40–49 119 60 (23.9) 59 (31.7)   4.8 (2.6–8.9)**
50–59 97 72 (28.7) 25 (13.4)   13.6 (7.0–26.7)**
≥ 60 112 100 (39.8) 12 (6.5)   39.5(18.2–85.8)**
Smoker Yes 196 93 (37.7) 103 (56.3) <0.001
(0.446)
0.5 (0.3–0.7)** 0.8(0.5–1.2)
No 234 154 (62.3) 80 (43.7)   1 1
Personal BC history Yes 13 12 (4.8) 1 (0.5) 0.009 (0.086) 9.3 (1.2–72.1)** 7.0(0.8–64.7)
No 424 239 (95.2) 185 (99.5)   1 1
Number of children 1+ 326 205 (81.7) 121 (65.1) <0.001
(0.465)
2.4 (1.5–3.7)** 1.0 (0.6–1.8)
None 111 46 (18.3) 65 (34.9)   1 1
Breastfeeding (months) 12+ 81 52 (27.2) 29 (25.2) 0.789 (0.139) 1.1 (0.6–1.9) 0.8 (0.4–1.5)
0–11 170 139 (72.8) 86 (74.8)   1 1
Menopausial status Yes 188 152 (62.0) 36 (19.7) <0.001 (0.238) 6.7 (4.2–10.4)** 0.7 (0.3–1.6)
No 240 93 (38.0) 147 (80.3)   1 1
Age at menopause (years) ≥ 54 25 24 (15.8) 1(2.8) 0.012 (0.179) 18 (1.9–173)** 7.5 (0.7–82.6)
42–53 149 120 (78.9) 29 (80.6)*   3.1 (0.9–9.6)* 1.8 (0.5–6.9)
≤ 41 14 8(5.3) 6 (16.7)   1 1
History of cervical diseases No 302 156 (95.7) 146 (91.8) 0.171 (0.288) 1.9 (0.8–5.1) 1.7 (0.6–4.8)
Yes 20 7 (4.3) 13 (8.2)   1 1
  1. OR Odd Ratio, AOR Adjusted Odd Ratio, BC Breast Cancer, CI 95% Confidence Interval 95%, * Statistic signification <0.05, ** Statistic Signification <0.01