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Fig. 3 | BMC Cancer

Fig. 3

From: Metformin produces growth inhibitory effects in combination with nutlin-3a on malignant mesothelioma through a cross-talk between mTOR and p53 pathways

Fig. 3

Combinatory effects of metformin and nutlin-3a. a Cells were treated with metformin, nutlin-3a or metformin plus nutlin-3a as indicated. Relative viability was calculated based on uninfected cells. Averages and SE bars are shown (n=3). b CI values in combination of metformin and nutlin-3a were calculated with CalcuSyn software at various Fa points. c Cell numbers were counted with a trypan blue dye exclusion assay after cells were treated with metformin, nutlin-3a or metformin plus nutlin-3a as indicated. Averages and SE bars are shown (n=3). *P<0.05

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BMC Cancer

ISSN: 1471-2407

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