Table 2 Univariate and multivariate analyses for RFS and CSS
RFS | CSS | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
variables | 5 yr. rate | p value | HR | 95% CI | p value | 5 yr. rate | p value | HR | 95% CI | p value |
size >4 cm | 0.304 | 0.073 | 2.781 | 0.710–10.990 | 0.142 | |||||
no | 92.0 | 93.9 | ||||||||
yes | 83.1 | 87.9 | ||||||||
SCC Ag | 0.611 | 0.904 | ||||||||
≤ 2 ng/mL | 88.0 | 89.9 | ||||||||
> 2 ng/mL | 86.9 | 91.2 | ||||||||
DSI | 0.985 | 0.778 | ||||||||
absent | 86.4 | 90.7 | ||||||||
present | 87.9 | 90.6 | ||||||||
LVSI | 0.671 | 0.720 | ||||||||
absent | 100.0 | 100.0 | ||||||||
present | 86.9 | 90.1 | ||||||||
PM invasion | 0.145 | 0.196 | ||||||||
absent | 85.7 | 89.2 | ||||||||
present | 100.0 | 100.0 | ||||||||
RM | 0.052 | 2.868 | 0.881–9.333 | 0.080 | 0.132 | |||||
clear | 92.8 | 92.7 | ||||||||
close or positive | 81.0 | 88.0 | ||||||||
LN metastasis | 0.664 | 0.932 | ||||||||
absent | 88.8 | 88.2 | ||||||||
present | 87.3 | 91.1 | ||||||||
No. of positive LN | 0.021 | 3.179 | 1.066–9.477 | 0.038 | 0.005 | 4.004 | 1.130–14.195 | 0.032 | ||
0–2 | 92.8 | 94.5 | ||||||||
≥ 3 | 74.1 | 81.5 | ||||||||
LNR | 0.018 | 2.330 | 0.611–8.879 | 0.215 | 0.011 | 1.740 | 0.391–7.740 | 0.467 | ||
< 0.25 | 90.7 | 91.8 | ||||||||
≥ 0.25 | 63.6 | 81.8 | ||||||||
No. of risk factors | 0.299 | 0.345 | ||||||||
1 | 90.8 | 90.7 | ||||||||
2–3 | 81.3 | 90.6 | ||||||||