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Table 2 Mammographic features of interval breast cancers at the latest screen and tumor size distribution

From: Interval breast cancer characteristics before, during and after the transition from screen-film to full-field digital screening mammography

 

A

SFM with prior SFM

B

FFDM with prior SFM

C

FFDM with prior FFDM

Missed interval cancers at latest screen, n

42

35

39

Mammographic abnormality at latest screen, n (%)

 Mass

28 (66.7)

23 (65.7)

27 (69.2)

 Calcifications

2 (4.8)

5 (14.3)

5 (12.8)

 Mass with calcifications

5 (11.9)

4 (11.4)

4 (10.3)

 Asymmetry

2 (4.8)

0 (0)

0 (0.0)

 Architectural distortion

5 (11.9)

3 (8.6)

3 (7.7)

Type of interval cancer, n (%)

 Ductal carcinoma in-situ

1 (2.4)

1 (2.9)

2 (5.1)

 Invasive cancer

41 (97.6)

34 (97.1)

37 (94.9)

Size distribution of invasive interval cancers, n (%)

 T1a-b

2 (4.9)

5 (14.7)

4 (10.8)

 T1c

15 (36.6)

8 (23.5)

9 (24.3)

 T2+

24 (58.5)

20 (58.8)

24 (64.9)

 Unknown

0 (0.0)

1 (2.9)

0 (0.0)

Mean size of invasive interval cancers, mm (range)

29.3 (8-80)

28.8 (2-100)

25.5 (6-120)

Breast density at latest screen, n (%)

 ACR I & II

23 (54.8)

21 (60.0)

23 (59.0)

 ACR III & IV

19 (45.2)

14 (40.0)

16 (41.0)

Minimal sign interval cancers at latest screen, n

31

20

20

Mammographic abnormality at latest screen, n (%)

 Mass

19 (61.3)

10 (50.0)

10 (50.0)

 Calcifications

7 (22.6)

2 (10.0)

2 (10.0)

 Mass with calcifications

0 (0.0)

2 (10.0)

0 (0.0)

 Asymmetry

3 (9.7)

1 (5.0)

5 (25.0)

 Architectural distortion, n (%)

2 (6.5)

5 (25.0)

3 (15.0)

Type of interval cancer, n (%)

 Ductal carcinoma in-situ

2 (6.5)

2 (10.0)

1 (5.0)

 Invasive cancer

29 (93.5)

18 (90.0)

19 (95.0)

Size distribution of invasive interval cancers, n (%)

 T1a-b

2 (6.9)

0 (0.0)

1 (5.3)

 T1c

13 (44.8)

8 (44.4)

7 (36.8)

 T2+

14 (48.3)

10 (55.6)

11 (57.9)

Mean size of invasive interval cancers, mm (range)

24.5 (1-60)

29.1 (11-80)

28.4 (5-60)

Breast density at latest screen, n (%)

 ACR I & II

21 (67.7)

14 (70.0)

11 (55.0)

 ACR III & IV

10 (32.2)

6 (30.0)

9 (45.0)

Occult interval cancers at latest screen

71

104

80

Type of interval cancer, n (%)

 Ductal carcinoma in-situ

5 (7.0)

6 (5.8)

5 (6.3)

 Invasive cancer

66 (93.0)

98 (94.2)

75 (93.8)

Size distribution of invasive interval cancers, n (%)

 T1a-b

12 (18.2)

15 (15.3)

12 (16.0)

 T1c

22 (33.3)

34 (34.7)

26 (34.7)

 T2+

32 (48.5)

48 (49.0)

33 (44.0)

 Unknown

0 (0.0)

1 (1.0)

4 (5.3)

Mean size of invasive interval cancers, mm (range)

21.8 (2-60)

25.3 (2-90)

23.2 (3-95)

Breast density at latest screen, n (%)

 ACR I & II

38 (53.5)

65 (62.5)

44 (55.0)

 ACR III & IV

33 (46.5)

39 (37.5)

36 (45.0)

  1. SFM screen-film mammography, FFDM full-field digital mammography, ACR American College of Radiology