Table 3 Correlations between the severity of microvascular invasion or portal vein tumor thrombus and viral features in hepatocellular carcinomaa
HBV-related factors | Severity of MVI | P | Classification of PVTT | P | ||||
|---|---|---|---|---|---|---|---|---|
None (%) | Mild (%) | Severe (%) | None (%) | I/II (%) | III/IV (%) | |||
Seral HBsAg | ||||||||
Positive | 171 (83.8) | 127 (89.4) | 131 (94.9) | 0.005* | 326 (86.2) | 74 (94.9) | 30 (100) | 0.007* |
Negative | 33 (16.2) | 15 (10.6) | 7 (5.1) | 52 (13.8) | 4 (5.1) | 0 (0) | ||
Seral HBeAg | ||||||||
Positive | 37 (21.6) | 38 (29.9) | 48 (36.6) | 0.016* | 84 (25.8) | 30 (40.5) | 9 (30) | 0.04* |
Negative | 134 (78.4) | 89 (60.1) | 83 (63.4) | 242 (74.2) | 44 (59.5) | 21 (70) | ||
Seral HBV DNA load | ||||||||
> 50 IU/ml | 99 (57.9) | 90 (70.9) | 106 (80.9) | <0.001* | 219 (67.2) | 52 (70.3) | 24 (80) | 0.355 |
< = 50 IU/ml) | 72 (42.1) | 37 (29.1) | 25 (19.1) | 107 (32.8) | 22 (29.7) | 6 (20) | ||
Presence of cirrhosis | ||||||||
Yes | 52 (30.4) | 48 (37.8) | 44 (33.6) | 0.418 | 96 (29.4) | 32 (43.2) | 16 (53.3) | 0.005* |
No | 119 (69.6) | 79 (62.2) | 87 (66.4) | 230 (60.6) | 42 (56.8) | 14 (46.7) | ||
Antivirus treatment | ||||||||
Yes | 66 (38.6) | 36 (28.3) | 26 (19.8) | 0.002* | 109 (33.4) | 15 (20.3) | 4 (13.3) | 0.009* |
No | 105 (61.4) | 91 (61.7) | 105 (80.2) | 217 (66.6) | 59 (79.7) | 26 (86.7) | ||