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Table 2 Association of clinicopathological characteristics and overall survival

From: Prognosis and treatment of non-metastatic primary and secondary breast angiosarcoma: a comparative study

  

Primary

  

Secondary

Parameters

HR

95% CI

p

HR

95% CI

p

Age (years)

      

  < 60

1

  

1

  

  ≥ 60

1.54

1.04–2.28

0.032

1.91

1.07–3.42

0.03

Race

      

 Non-white

1

  

1

  

 White

1.47

0.85–2.53

0.169

1.33

0.62–2.87

0.464

Site

      

 Outer quandrant

1

  

1

  

 Inner Quandrant

0.82

0.43–1.58

0.549

1.51

0.68–3.34

0.307

 Central

0.6

0.22–1.61

0.311

0.97

0.38–2.47

0.94

 Overlapa

1.45

0.83–2.53

0.191

1.07

0.56–2.05

0.841

 NOSb

1

0.56–1.77

0.988

0.75

0.43–1.32

0.315

 Nipple

    

Not calculated

 

Tumor spread

      

 Local

1

  

1

  

 Regional

2.66

1.69–4.19

<0.001

1.83

1.23–2.72

0.003

Tumor grade

      

 G1

1

  

1

  

 G2

1.14

0.53–2.44

0.746

1.79

0.65–4.98

0.263

 G3

3.73

1.88–7.43

<0.001

2.16

0.87–5.34

0.097

 Gx

1.6

0.79–3.26

0.196

1.31

0.48–3.52

0.598

Number of primariesc

      

 1 (2)

1

  

1

  

  ≥ 2 (≥ 3)

1.04

0.64–1.70

0.866

1.3

0.88–1.93

0.191

  1. aMore than one quandrant but less than half breast size
  2. bEntire breast: ¾ or more of breast involved with tumor, or multiple tumors in different subsites
  3. cComparisons were made in 1 versus ≥2 primary tumor groups in primary angiosarcoma and in 2 versus ≥3 primary tumor groups in secondary angiosarcoma