TY - JOUR AU - Levan, Kristina AU - Mehryar, Matin AU - Mateoiu, Constantina AU - Albertsson, Per AU - Bäck, Tom AU - Sundfeldt, Karin PY - 2017 DA - 2017/05/02 TI - Immunohistochemical evaluation of epithelial ovarian carcinomas identifies three different expression patterns of the MX35 antigen, NaPi2b JO - BMC Cancer SP - 303 VL - 17 IS - 1 AB - To characterize the expression of the membrane transporter NaPi2b and antigen targeted by the MX35 antibody in ovarian tumor samples. The current interest to develop monoclonal antibody based therapy of ovarian cancer by targeting NaPi2b emphasizes the need for detailed knowledge and characterization of the expression pattern of this protein. For the majority of patients with ovarian carcinoma the risk of being diagnosed in late stages with extensive loco-regional spread disease is substantial, which stresses the need to develop improved therapeutic agents. SN - 1471-2407 UR - https://doi.org/10.1186/s12885-017-3289-2 DO - 10.1186/s12885-017-3289-2 ID - Levan2017 ER -