Table 3 Most common TEAEs by grade
TEAE occurring in >10% of patients, n (%)a | NCI CTCAE grade (n = 104) | |||||
|---|---|---|---|---|---|---|
Total | 1 | 2 | 3 | 4 | 5 | |
Any AE | 104 (100.0) | 8 (7.7) | 37 (35.6) | 37 (35.6) | 13 (12.5) | 8 (7.7) |
Muscle spasms | 74 (71.2) | 45 (43.3) | 23 (22.1) | 6 (5.8) | 0 | 0 |
Alopecia | 69 (66.3) | 49 (47.1) | 20 (19.2) | NA | NA | NA |
Dysgeusia | 58 (55.8) | 32 (30.8) | 26 (25.0) | NA | NA | NA |
Weight decreased | 54 (51.9) | 29 (27.9) | 16 (15.4) | 9 (8.7) | NA | NA |
Fatigue | 45 (43.3) | 33 (31.7) | 7 (6.7) | 4 (3.8) | 1 (1.0) | 0 |
Nausea | 34 (32.7) | 25 (24.0) | 9 (8.7) | 0 | 0 | 0 |
Decreased appetite | 29 (27.9) | 19 (18.3) | 7 (6.7) | 3 (2.9) | 0 | 0 |
Diarrhea | 28 (26.9) | 20 (19.2) | 5 (4.8) | 3 (2.9) | 0 | 0 |
Constipation | 20 (19.2) | 14 (13.5) | 6 (5.8) | 0 | 0 | 0 |
Cough | 20 (19.2) | 16 (15.4) | 4 (3.8) | 0 | NA | NA |
Vomiting | 18 (17.3) | 15 (14.4) | 3 (2.9) | 0 | 0 | 0 |
Arthralgia | 17 (16.3) | 12 (11.5) | 4 (3.8) | 1 (1.0) | 0 | 0 |
Headache | 15 (14.4) | 12 (11.5) | 3 (2.9) | 0 | NA | NA |
Nasopharyngitis | 13 (12.5) | 11 (10.6) | 2 (1.9) | 0 | 0 | 0 |
SCC | 12 (11.5) | 3 (2.9) | 5 (4.8) | 3 (2.9) | 0 | 0 |
Ageusia | 12 (11.5) | 8 (7.7) | 4 (3.8) | NA | NA | NA |
Hypogeusia | 11 (10.6) | 10 (9.6) | 1 (1.0) | NA | NA | NA |
Pruritus | 11 (10.6) | 8 (7.7) | 2 (1.9) | 1 (1.0) | NA | NA |
Dyspepsia | 11 (10.6) | 8 (7.7) | 3 (2.9) | 0 | NA | NA |