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Table 3 Univariate analysis of risk factors associated with death related to interstitial lung disease induced by anticancer agents

From: Surfactant protein-D predicts prognosis of interstitial lung disease induced by anticancer agents in advanced lung cancer: a case control study

  Overall Survival Death Odds ratio 95% CI p
Overall 36 22 14    
Age     2.45 0.64–9.37 0.310
  ≤ 70 19 12 7    
  ≥ 71 17 10 7    
Sex     0.74 0.16–3.39 0.693
 Female 9 5 4    
 Male 27 17 10    
Performance status     1.22 0.44–3.43 0.693
 0–1 27 16 11    
 2–4 9 6 3    
Smoking history     2.48 1.26–4.86 0.042
 No 5 1 4    
 Yes 31 21 10    
With emphysema     1.50 0.67–3.39 0.334
 No 13 6 7    
 Yes 23 16 7    
With pre-existing interstitial shadow     1.67 0.73–3.81 0.221
 No 15 8 7    
 Yes 21 14 7    
ΔSP-D     7.00 2.19–72.26 0.001
  < 398 27 21 6    
  ≥ 398 9 1 8    
  1. Abbreviations: CI confidence interval, SP-D surfactant protein-D