TUmor-volume to breast-volume RAtio for improving COSmetic results in breast cancer patients (TURACOS); a randomized controlled trial

Table 2 Assessments and used instruments with timeframe indication

Outcome(s)	Instrument(s)	T0	T1	T2	T3
Primary endpoint
Cosmetic result	Evaluation clinical photos by panel - ‘Erasmus MC panels’ questionnaire’	x		x	x
Secondary outcome
Cosmetic result/satisfaction with breast assessed by patient	Breast Q - preoperative module	x
	Breast Q - postoperative module		x	x	x
Patients’ Quality of life	EORTC QLQ-C30/B23 questionnaire	x	x	x	x
	EQ-5D-5 L questionnaire	x	x	x	x
Cosmetic result BCCT.core	BCCT.core software (INESC Porto Breast Research Group)	x		x	x
Radiation-induced reaction	RTOG/EORTC			x	x
Surgical strategy performed	Performed surgery/surgeries				x
Pathological result	Data of pathology reports				x
Cost-effectiveness	Quality-Adjusted Life Year (QALY) for direct and indirect costs				x

T0 = first visit outpatient clinic, T1 = 3 months postoperative, T2 = 1 year postoperative, T3 = 3 years postoperative

ISSN: 1471-2407